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pyrimidine deoxyribonucleotide biosynthetic process

Known as: pyrimidine deoxyribonucleotide synthesis, pyrimidine deoxyribonucleotide biosynthesis, pyrimidine deoxyribonucleotide anabolism 
The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine… 
National Institutes of Health

Papers overview

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2012
2012
Elevated Ribonucleotide Reductase Levels Associate With Suppressed Radiochemotherapy Response in Human Cervical Cancers
Objective Ribonucleotide reductase (RNR) supplies deoxyribonucleotide diphosphates demanded by cells to repair radiation-induced… 
Highly Cited
2010
Highly Cited
2010
Ribonucleotide Reductase Inhibition Enhances Chemoradiosensitivity of Human Cervical Cancers
Abstract For repair of damaged DNA, cells increase de novo synthesis of deoxyribonucleotide triphosphates through the rate… 
2003
2003
Overexpression of the R2 Subunit of Ribonucleotide Reductase in Human Nasopharyngeal Cancer Cells Reduces Radiosensitivity
PURPOSERibonucleotide reductase is the rate-limiting enzyme in the de novo synthesis of deoxyribonucleotide triphosphates, which… 
Highly Cited
1997
Highly Cited
1997
Demethylation of DNA by purified chick embryo 5-methylcytosine-DNA glycosylase requires both protein and RNA.
We have previously purified and characterized a 5-methylcytosine (5-MeC)-DNA glycosylase from 12 day old chick embryos [Jost,J.P… 
Highly Cited
1993
Highly Cited
1993
Influence of 5'-nearest neighbors on the insertion kinetics of the fluorescent nucleotide analog 2-aminopurine by Klenow fragment.
The effects of nearest neighbor interactions between a nucleotide base at the primer 3'-terminus and an incoming… 
Highly Cited
1982
Highly Cited
1982
Are DNA precursors concentrated at replication sites?
We have asked whether the effective concentrations of deoxyribonucleotide 5'-triphosphates (dNTPs) at sites of DNA replication in… 
Highly Cited
1978
Highly Cited
1978
Animal cells reversibly permeable to small molecules.
A cell preparation, useful for studying the regulation of metabolism, was developed by making monolayer baby hamster kidney cells… 
1977
1977
Regulation of deoxyribonucleotide biosynthesis during in vivo bacteriophage T4 DNA replication. Intrinsic control of synthesis of thymine and 5-hydroxymethylcytosine deoxyribonucleotides at precise…
1974
1974
The repair of single-strand breaks in a radiosensitive mutant of Micrococcus radiodurans.
The kinetics of x-ray-induced single-strand break rejoinirg have been studied in wild-type M. radiodurans and a radiosensitive… 
1972
1972
Covalent Linkage Between Ribonucleic Acid Primer and Deoxyribonucleic Acid Product of the Avian Myeloblastosis Virus Deoxyribonucleic Acid Polymerase
Initiation of deoxyribonucleic acid (DNA) synthesis by the avian myeloblastosis virus DNA polymerase was previously suggested to… 
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