purinoceptor P2X4

Known as: P2X4 Purinoceptor, P2X4 Receptors, Purinergic, Receptor, P2X4 
A widely distributed purinergic P2X receptor subtype that plays a role in pain sensation. P2X4 receptors found on MICROGLIA cells may also play a… (More)
National Institutes of Health

Papers overview

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2014
2014
In response to neuronal injury or disease, microglia adopt distinct reactive phenotypes via the expression of different sets of… (More)
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Review
2012
Review
2012
ATP, acting via P2 purinergic receptors, is a known mediator of inflammatory and neuropathic pain. There is increasing evidence… (More)
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Highly Cited
2009
Highly Cited
2009
Microglia in the dorsal horn of the spinal cord are increasingly recognized as being crucial in the pathogenesis of pain… (More)
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Highly Cited
2009
Highly Cited
2009
Opioids, although fundamental to the treatment of pain, are limited in efficacy by side effects including tolerance and… (More)
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2005
2005
Following spinal cord injury (SCI), neuropathic, chronic pain is a major cause of disability. Recently, glial P2X4 receptor… (More)
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2003
2003
A monoclonal antibody was developed to the extracellular domain of the rat P2X4 receptor. The antibody was highly selective among… (More)
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2003
2003
In the present work we examined the involvement of selected P2X receptors for extracellular ATP in the onset of neuronal cell… (More)
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2000
2000
The rat ATP P2X4 receptor was expressed in Xenopus laevis oocytes to assess the effect of zinc and copper as possible regulators… (More)
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2000
2000
Ca(2+) signaling plays an important role in endothelial cell (EC) responses to shear stress generated by blood flow. Our previous… (More)
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1999
1999
Differential Modulation by Copper and Zinc of P2X2 and P2X4 Receptor Function. The modulation by Cu2+ and Zn2+ of P2X2 and P2X4… (More)
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