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purine antagonist

Known as: Purine Inhibitors 
An antimetabolite that affects the metabolism and utilization of purines.
National Institutes of Health

Papers overview

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2013
2013
Antagonists of the CB1 receptor can be useful in the treatment of several important disorders. However, to date, the only… Expand
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2013
2013
CDK2, which interacts with cyclin A and cyclin E, is an important member of the CDK family. Having been proved to be associated… Expand
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2011
2011
Small molecular inhibitors of Cyclin dependent kinases (Cdks) are currently being developed as anticancer therapeutics due to… Expand
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2010
2010
A series of 8-arylated purine derivatives bearing either an aniline or an alkyl amide at position 6 were found to inhibit… Expand
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2010
2010
Series of purine and pyrazolo[3,4-d]pyrimidine inhibitors of phosphatidylinositol-3-kinases (PI3K) have been prepared. The… Expand
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2005
2005
GOAL To assess the outcomes of empiric therapy with mycophenolate mofetil in patients with autoimmune hepatitis. BACKGROUND… Expand
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2004
2004
A series of purine based inhibitors of PDE7 has been derived from screening lead 1a. The synthesis, structure-activity… Expand
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1996
1996
The functional role in allosteric regulation of a flexible loop (residues 280-288) located near the active site of muscle… Expand
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1982
1982
The possibility that purine inhibitors or analogs might be effective antileishmanial agents led to the determination of the… Expand
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1959
1959
Extensive efforts by the Burroughs-Wellcome group, the Sloan-Kettering group, and others have led to a considerable knowledge of… Expand
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