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pseudoproline

Known as: psiPro 
National Institutes of Health

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3 relations

Broader (2)

ProlineThiazoles
analogs & derivatives

Papers overview

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2018
2018
The Pseudoproline Approach to Peptide Cyclization
The development of efficient methods for the synthesis of cyclic peptides is of interest because of the many potential… 
2015
2015
Synthesis of Dichotomin A: Use of a Penicillamine-Derived Pseudoproline to Furnish Native Valine Residues
The total synthesis of cyclic hexapeptide dichotomin A from linear peptide precursors containing penicillamine-derived… 
2014
2014
Synthesis of a stable isotopically labeled universal surrogate peptide for use as an internal standard in LC-MS/MS bioanalysis of human IgG and Fc-fusion protein drug candidates.
The synthesis of a 16-residue, stable isotopically labeled peptide is described for use as a LC-MS/MS (Liquid chromatography-mass… 
2010
2010
Slightly modifying pseudoproline dipeptides incorporation strategy enables solid phase synthesis of a 54 AA fragment of caveolin‐1 encompassing the intramembrane domain
This work contributes to highlight the benefits of pseudoproline dipeptides introduction in difficult SPPS. We show how a slight… 
2007
2007
Fast Fmoc synthesis of hAmylin1–37 with pseudoproline assisted on‐resin disulfide formation
Human amylin (1–37) and the (1–13) fragment were synthesized with and without pseudoproline dipeptides. Thallium (III… 
2007
2007
Solid Phase Synthesis of Phosphopeptides Incorporating 2,2-Dimethyloxazolidine Pseudoproline Analogs: Evidence for trans Leu-Pro Peptide Bonds in Stat3 Inhibitors
To answer the question of whether the conformation of the Leu-Pro bond is cis or trans in Ac-pTyr-Leu-Pro-Gln-Thr-Val-NH2 when… 
2005
2005
A Novel Route to Pseudoproline (ΨH,HPro)-Containing Dipeptides Building Blocks
In view of the synthetic and biological interest of pseudoproline (ΨR,RPro)-containing peptides, we have investigated a new… 
2003
2003
Development and conformational analysis of a pseudoproline-containing turn mimic.
The liquid-phase synthesis and the conformational analysis of a small library of fully protected tetramers containing L… 
2000
2000
Pseudoprolines (psiPro) in drug design: direct insertion of psiPro systems into cyclosporin C.
The insertion of acetals that exhibit variable structural features into complex peptides such as cyclosporin C (CsC) results in… 
Highly Cited
1999
Highly Cited
1999
The synthesis of ‘difficult’ peptides using 2‐hydroxy‐4‐methoxybenzyl or pseudoproline amino acid building blocks: a comparative study
A comparative study has been undertaken between Hmb‐protected amino acid and pseudoproline building block analogues for use in… 
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