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pseudoproline

Known as: psiPro 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

ProlineThiazoles
analogs & derivatives

Papers overview

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Highly Cited
2012
Highly Cited
2012
Convergent solid-phase synthesis of N-glycopeptides facilitated by pseudoprolines at consensus-sequence Ser/Thr residues.
N-Glycosylation is an important posttranslational modification of proteins. A carbohydrate is transferred to an asparagine within… 
Highly Cited
2010
Highly Cited
2010
Chemical Synthesis of Ubiquitin, Ubiquitin-Based Probes, and Diubiquitin**
Post-translational modification of proteins with ubiquitin (Ub) and Ub chains controls protein breakdown by the proteasome… 
2010
2010
Synthesis of all-L cyclic tetrapeptides using pseudoprolines as removable turn inducers.
Cyclic tetrapeptides have generated great interest because of their broad-ranging biological properties. In order to synthesize… 
2007
2007
Fast Fmoc synthesis of hAmylin1–37 with pseudoproline assisted on‐resin disulfide formation
Human amylin (1–37) and the (1–13) fragment were synthesized with and without pseudoproline dipeptides. Thallium (III… 
Highly Cited
2006
Highly Cited
2006
The synergy of ChemMatrix resin and pseudoproline building blocks renders RANTES, a complex aggregated chemokine.
Traditionally, solid-phase synthesis has relied on polystyrene-based resins for the synthesis of all kinds of peptides. However… 
Highly Cited
2005
Highly Cited
2005
Incorporation of pseudoproline derivatives allows the facile synthesis of human IAPP, a highly amyloidogenic and aggregation-prone polypeptide.
The efficient Fmoc solid-phase peptide synthesis of the 37-residue human Amylin and its amyloidogenic 8-37 fragment was achieved… 
Highly Cited
2001
Highly Cited
2001
Pseudoproline-containing analogues of morphiceptin and endomorphin-2: evidence for a cis Tyr-Pro amide bond in the bioactive conformation.
Analogues of the opioid peptides [D-Phe(3)]morphiceptin (H-Tyr-Pro-D-Phe-Pro-NH(2)) and endomorphin-2 (H-Tyr-Pro-Phe-Phe-NH(2… 
Highly Cited
1999
Highly Cited
1999
Pseudo-prolines: induction of cis/trans-conformational interconversion by decreased transition state barriers.
Molecular events such as cis/trans isomerization of Xaa-Pro tertiary amide bonds in peptides and proteins are slow on the overall… 
Highly Cited
1999
Highly Cited
1999
The synthesis of ‘difficult’ peptides using 2‐hydroxy‐4‐methoxybenzyl or pseudoproline amino acid building blocks: a comparative study
A comparative study has been undertaken between Hmb‐protected amino acid and pseudoproline building block analogues for use in… 
Highly Cited
1994
Highly Cited
1994
Peptide segment ligation strategy without use of protecting groups.
  • C. F. LiuJ. Tam
  • Proceedings of the National Academy of Sciences…
  • 1994
  • Corpus ID: 2351983
We describe the concept and the verification of a chemical ligation approach to the synthesis of proteins using peptide segments… 
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