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proxyphylline

Known as: Beta-Oxypropyltheophyllin, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-(2-hydroxypropyl)-, 1,3-Dimethyl-7-(2-hydroxypropyl)xanthine 
A methylxanthine and derivative of theophylline. Proxyphylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely… 
National Institutes of Health

Related topics

Related topics

4 relations
Aminophyllineanalogs & derivatives

Broader (2)

Bronchodilator AgentsTheophylline

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Chemoenzymatic Synthesis of Proxyphylline Enantiomers.
A novel synthetic route for preparation of proxyphylline enantiomers using a kinetic resolution (KR) procedure as the key step is… 
Highly Cited
2012
Highly Cited
2012
Evaluation of postmortem redistribution phenomena for commonly encountered drugs.
2009
2009
Simultaneous and specific determination of proxyphylline, theophylline and other xanthine derivatives in serum by high pressure liquid chromatography.
A HPLC-method for rapid, simultaneous and specific determination of proxyphylline, theophylline, glyphylline, theobromine… 
2002
2002
Minimization of initial burst in poly(vinyl alcohol) hydrogels by surface extraction and surface-preferential crosslinking.
Highly Cited
2002
Highly Cited
2002
Polymer particle erosion controlling drug release. II. Swelling investigations to clarify the release mechanism.
Highly Cited
1999
Highly Cited
1999
Highly crosslinked, PEG-containing copolymers for sustained solute delivery.
Highly Cited
1999
Highly Cited
1999
Solute transport analysis in pH-responsive, complexing hydrogels of poly(methacrylic acid-g-ethylene glycol).
  • A. LowmanN. Peppas
  • Journal of Biomaterials Science. Polymer Edition
  • 1999
  • Corpus ID: 23303183
We report on the preparation and properties of hydrogels of poly(methacrylic acid-g-ethylene glycol) that exhibit pH-responsive… 
Highly Cited
1993
Highly Cited
1993
Porogens in the preparation of microporous hydrogels based on poly(ethylene oxides).
Highly Cited
1993
Highly Cited
1993
Release behavior of bioactive agents from pH-sensitive hydrogels.
  • A. KhareN. Peppas
  • Journal of Biomaterials Science. Polymer Edition
  • 1993
  • Corpus ID: 28839815
Controlled release systems of theophylline, proxyphylline and oxprenolol.HCl exhibiting modulated drug delivery were prepared by… 
1988
1988
Methylxanthines inhibit exercise-induced bronchoconstriction at low serum theophylline concentration and in a dose-dependent fashion.
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