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proxyphylline

Known as: Beta-Oxypropyltheophyllin, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-(2-hydroxypropyl)-, 1,3-Dimethyl-7-(2-hydroxypropyl)xanthine 
A methylxanthine and derivative of theophylline. Proxyphylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Aminophyllineanalogs & derivatives

Broader (2)

Bronchodilator AgentsTheophylline

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Chemoenzymatic Synthesis of Proxyphylline Enantiomers.
A novel synthetic route for preparation of proxyphylline enantiomers using a kinetic resolution (KR) procedure as the key step is… Expand
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Highly Cited
2012
Highly Cited
2012
Evaluation of postmortem redistribution phenomena for commonly encountered drugs.
We described the findings of a study into the post-mortem redistribution (PMR) of 76 drugs found in 129 drug-related cases… Expand
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2008
2008
Modifying the release of proxyphylline from PVA hydrogels using surface crosslinking.
Drug release profiles were altered to prevent the initial burst effect or introduce a lag phase by creating surface crosslinked… Expand
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2008
2008
Surface crosslinking for delayed release of proxyphylline from PHEMA hydrogels.
Delayed release systems find applications in chronotherapeutics and colon-specific delivery. They have also been considered… Expand
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2004
2004
Effect of Polymeric Network Structure on Drug Release from Cross-Linked Poly(Vinyl Alcohol) Micromatrices
Three types of poly(vinyl alcohol) were cross-linked by glutaraldehyde to form water-swellable materials possessing a three… Expand
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Highly Cited
1999
Highly Cited
1999
Highly crosslinked, PEG-containing copolymers for sustained solute delivery.
Novel ionizable polymer networks were prepared from oligo(ethylene glycol) (OEG) multiacrylates and acrylic acid (AA) employing… Expand
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1999
1999
Solute transport analysis in pH-responsive, complexing hydrogels of poly(methacrylic acid-g-ethylene glycol).
  • A. Lowman, N. Peppas
  • Journal of biomaterials science. Polymer edition
  • 1999
    • Corpus ID: 23303183
We report on the preparation and properties of hydrogels of poly(methacrylic acid-g-ethylene glycol) that exhibit pH-responsive… Expand
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Highly Cited
1993
Highly Cited
1993
Release behavior of bioactive agents from pH-sensitive hydrogels.
Controlled release systems of theophylline, proxyphylline and oxprenolol.HCl exhibiting modulated drug delivery were prepared by… Expand
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Highly Cited
1993
Highly Cited
1993
Porogens in the preparation of microporous hydrogels based on poly(ethylene oxides).
To enable the synthesis of hydrogels containing microporosity, a family of pore generating additives (porogens) were synthesized… Expand
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1992
1992
Composite Poly(vinyl alcohol) Beads for Controlled Drug Delivery
A new method of preparing composite poly(vinyl alcohol) (PVA) beads with a double-layer structure has been developed, which… Expand
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