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proxyphylline

Known as: Beta-Oxypropyltheophyllin, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-7-(2-hydroxypropyl)-, 1,3-Dimethyl-7-(2-hydroxypropyl)xanthine 
A methylxanthine and derivative of theophylline. Proxyphylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely… 
National Institutes of Health

Related topics

Related topics

4 relations
Aminophyllineanalogs & derivatives

Broader (2)

Bronchodilator AgentsTheophylline

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Evaluation of postmortem redistribution phenomena for commonly encountered drugs.
We described the findings of a study into the post-mortem redistribution (PMR) of 76 drugs found in 129 drug-related cases… 
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2008
2008
Modifying the release of proxyphylline from PVA hydrogels using surface crosslinking.
Drug release profiles were altered to prevent the initial burst effect or introduce a lag phase by creating surface crosslinked… 
2008
2008
Surface crosslinking for delayed release of proxyphylline from PHEMA hydrogels.
Delayed release systems find applications in chronotherapeutics and colon-specific delivery. They have also been considered… 
Highly Cited
2002
Highly Cited
2002
Polymer particle erosion controlling drug release. II. Swelling investigations to clarify the release mechanism.
The aim of the study was a comprehensive swelling investigation of hydrocolloid tablets with drug release by diffusion, erosion… 
Highly Cited
1999
Highly Cited
1999
Highly crosslinked, PEG-containing copolymers for sustained solute delivery.
Novel ionizable polymer networks were prepared from oligo(ethylene glycol) (OEG) multiacrylates and acrylic acid (AA) employing… 
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Highly Cited
1999
Highly Cited
1999
Solute transport analysis in pH-responsive, complexing hydrogels of poly(methacrylic acid-g-ethylene glycol).
  • A. Lowman, N. Peppas
  • Journal of biomaterials science. Polymer edition
  • 1999
  • Corpus ID: 23303183
We report on the preparation and properties of hydrogels of poly(methacrylic acid-g-ethylene glycol) that exhibit pH-responsive… 
Highly Cited
1993
Highly Cited
1993
Release behavior of bioactive agents from pH-sensitive hydrogels.
  • A. Khare, N. Peppas
  • Journal of biomaterials science. Polymer edition
  • 1993
  • Corpus ID: 28839815
Controlled release systems of theophylline, proxyphylline and oxprenolol.HCl exhibiting modulated drug delivery were prepared by… 
Highly Cited
1993
Highly Cited
1993
Porogens in the preparation of microporous hydrogels based on poly(ethylene oxides).
To enable the synthesis of hydrogels containing microporosity, a family of pore generating additives (porogens) were synthesized… 
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1983
1983
Simultaneous determination of diprophylline, proxyphylline and theophylline in serum by reversed-phase high-performance liquid chromatography.
A selective and reliable high-performance liquid chromatographic assay for the simultaneous determination of diprophylline… 
1978
1978
Simultaneous and specific determination of proxyphylline, theophylline and other xanthine derivatives in serum by high pressure liquid chromatography.
A HPLC-method for rapid, simultaneous and specific determination of proxyphylline, theophylline, glyphylline, theobromine… 
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