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protylonolide

Known as: Tylonolide, 20-deoxo-23-deoxy- 
 
National Institutes of Health

Papers overview

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2001
2001
Tylosin is produced by Streptomyces fradiae via a combination of polyketide metabolism and synthesis of three deoxyhexose sugars… Expand
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1986
1986
A resting cell system was used to study the sites of inhibition by NH4+ of protylonolide biosynthesis by a blocked mutant, strain… Expand
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Highly Cited
1984
Highly Cited
1984
The production of tylosin by Streptomyces fradiae KA-427 in a defined medium was inhibited by ammonium ions and by inorganic… Expand
1984
1984
Protylonolide is a lactonic precursor of tylosin aglycone, produced by a mutant of Streptomyces fradiae. It originates from n… Expand
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Highly Cited
1983
Highly Cited
1983
Sir: The biosynthesis of macrolide antibiotics is inhibited by ammonium ions.1) Previous papersl~3) from this laboratory reported… Expand
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1983
1983
Sir: Microbial conversion of antibiotically inactive macrocyclic lactones to active compounds is an important approach in the… Expand
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1983
1983
In previous papers1,2) we described the derivation of new macrolide antibiotics using the technique of hybrid biosynthesis. In a… Expand
1982
1982
Biotransformation of a macrolide antibiotic and a related compound was studied using various macrolide-producing microorganisms… Expand
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1982
1982
5-O-Mycarosyltylactone has been isolated as a predominant factor from fermentation broths of a Streptomyces fradiae mutant. The… Expand