prothrombin complex concentrates

Known as: PPSB, cofact, factor IX concentrate 
 
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Four-factor prothrombin complex concentrates (PCCs), which contain factor II, FVII, FIX, and FX, have shown the… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND One limitation of the direct thrombin inhibitor dabigatran is the lack of specific antidotes that allow acute bleeding… (More)
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2012
2012
BACKGROUND There is uncertainty regarding the efficacy and incidence of thromboembolic events in patients treated with… (More)
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2011
2011
Warfarin is a commonly prescribed anticoagulant that may, in selected situations, require rapid reversal of its effects. Several… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Fresh frozen plasma (FFP) and prothrombin complex concentrates (PCC) reverse oral anticoagulants. We compared PCC and… (More)
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2008
2008
AIMS A number of prothrombin complex concentrates (PCCs) are commercially available but they differ in terms of composition. We… (More)
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Highly Cited
2007
Highly Cited
2007
INTRODUCTION Rapid reversal of anticoagulant effect from the use of vitamin K antagonists (VKA) is essential when acute bleeding… (More)
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2004
2004
Prothrombin complex concentrates (PCC) were compared in an in vitro test system for thrombogenicity (thrombin generation assay… (More)
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Review
1999
Review
1999
Haemophilia patients with inhibitors are treated for acute bleeding with prothrombin complex concentrates (PCCs) or activated… (More)
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1999
1999
Objective: To evaluate thrombogenicity of prothrombin complex concentrates (PCCs) in critically ill patients.¶Design: Prospective… (More)
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