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prothrombin complex concentrates
Known as:
PPSB
, cofact
, factor IX concentrate
National Institutes of Health
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Related topics
Related topics
9 relations
ANTI-INHIBITOR COAGULANT COMPLEX
factor IX complex
Broader (2)
Blood Coagulation Factor
prothrombin complex
Narrower (5)
Konyne
Octaplex
Proplex
Prothrombinex
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate
A. Majeed
,
K. Meijer
,
+4 authors
S. Schulman
Thrombosis and Haemostasis
2013
Corpus ID: 38931863
Summary Prothrombin complex concentrates (PCC) can rapidly normalise prolonged prothrombin time, induced by vitamin K antagonists…
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2012
2012
Prothrombin complex concentrate (Octaplex): a Portuguese experience in 1152 patients
M. Carvalho
,
A. Rodrigues
,
L. Conceição
,
M. Galvão
,
L. C. Ribeiro
Blood Coagulation and Fibrinolysis
2012
Corpus ID: 9340047
In emergency/clinical practice it is often necessary to restore the balance of blood coagulation: the rapid reversal of oral…
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Review
2012
Review
2012
Perioperative use of prothrombin complex concentrates.
M. Colomina
,
A. DíezLobo
,
I. Garutti
,
A. Gómez-Luque
,
L. Jv
,
E. Pita
Minerva Anestesiologica
2012
Corpus ID: 25971682
Prothrombin complex concentrates (PCCs) are purified drug products with hemostatic activity derived from a plasma pool. Today…
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2006
2006
Proteomics as a tool for assessment of therapeutics in transfusion medicine: evaluation of prothrombin complex concentrates
Matthias Brigulla
,
T. Thiele
,
+4 authors
A. Greinacher
Transfusion
2006
Corpus ID: 25282736
BACKGROUND: Proteomic technologies are evolving tools to analyze complex protein patterns that to date have been rarely applied…
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1996
1996
High Purity Factor IX and Prothrombin Complex Concentrate (PCC): Pharmacokinetics and Evidence that Factor IXa Is the Thrombogenic Trigger in PCC
H. Philippou
,
A. Adami
,
+5 authors
C. Ludlam
Thrombosis and Haemostasis
1996
Corpus ID: 37775342
Summary Recent studies using assays for surrogate markers of thrombogenic-ity in man have demonstrated that activation of the…
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Highly Cited
1995
Highly Cited
1995
Measurement of Activated Factor IX in Factor IX Concentrates: Correlation with In Vivo Thrombogenicity
E. Gray
,
J. Tubbs
,
+4 authors
T. Barrowcliffe
Thrombosis and Haemostasis
1995
Corpus ID: 31236467
Summary Current in vitro tests for thrombogenicity of FIX concentrates used for prothrombin complex concentrates (PCCs), are of…
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Highly Cited
1991
Highly Cited
1991
No activation of the common pathway of the coagulation cascade after a highly purified factor IX concentrate
P. Mannucci
,
K. Bauer
,
+4 authors
R. Rosenberg
British Journal of Haematology
1991
Corpus ID: 33424140
Purer factor IX concentrates, containing very little or no factor II or X, have been developed in an attempt to avoid the…
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Highly Cited
1990
Highly Cited
1990
Thrombin generation is not increased in the blood of hemophilia B patients after the infusion of a purified factor IX concentrate.
P. Mannucci
,
K. Bauer
,
+4 authors
R. Rosenberg
Blood
1990
Corpus ID: 12967191
Prothrombin complex concentrates (PCC), licensed for the treatment of hemophilia B, are known to carry a significant risk of…
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1980
1980
Increased Fibrinopeptide A after Prothrombin Complex Concentrates
S. Viganó
,
M. Cattaneo
,
W. Gervasoni
,
P. Mannucci
Thrombosis and Haemostasis
1980
Corpus ID: 41521702
Summary Prothrombin complex concentrates (PCC) are known to carry a risk of thromboembolism. We have chosen to reassess the…
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1978
1978
Use of prothrombin complex concentrates in hemophiliacs with inhibitors: clinical and laboratory studies.
G. Buchanan
,
S. Kevy
Pediatrics
1978
Corpus ID: 38527000
Nine patients with severe classic hemophilia and inhibitors against factor VIII were treated for 156 bleeding episodes with 503…
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