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prothrombin complex concentrates

Known as: PPSB, cofact, factor IX concentrate 
National Institutes of Health

Related topics

Related topics

9 relations
ANTI-INHIBITOR COAGULANT COMPLEXfactor IX complex

Broader (2)

Blood Coagulation Factorprothrombin complex

Narrower (5)

KonyneOctaplexProplexProthrombinex

Papers overview

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Highly Cited
2013
Highly Cited
2013
Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate
Summary Prothrombin complex concentrates (PCC) can rapidly normalise prolonged prothrombin time, induced by vitamin K antagonists… 
2012
2012
Prothrombin complex concentrate (Octaplex): a Portuguese experience in 1152 patients
In emergency/clinical practice it is often necessary to restore the balance of blood coagulation: the rapid reversal of oral… 
Review
2012
Review
2012
Perioperative use of prothrombin complex concentrates.
Prothrombin complex concentrates (PCCs) are purified drug products with hemostatic activity derived from a plasma pool. Today… 
2006
2006
Proteomics as a tool for assessment of therapeutics in transfusion medicine: evaluation of prothrombin complex concentrates
BACKGROUND:  Proteomic technologies are evolving tools to analyze complex protein patterns that to date have been rarely applied… 
1996
1996
High Purity Factor IX and Prothrombin Complex Concentrate (PCC): Pharmacokinetics and Evidence that Factor IXa Is the Thrombogenic Trigger in PCC
Summary Recent studies using assays for surrogate markers of thrombogenic-ity in man have demonstrated that activation of the… 
Highly Cited
1995
Highly Cited
1995
Measurement of Activated Factor IX in Factor IX Concentrates: Correlation with In Vivo Thrombogenicity
Summary Current in vitro tests for thrombogenicity of FIX concentrates used for prothrombin complex concentrates (PCCs), are of… 
Highly Cited
1991
Highly Cited
1991
No activation of the common pathway of the coagulation cascade after a highly purified factor IX concentrate
Purer factor IX concentrates, containing very little or no factor II or X, have been developed in an attempt to avoid the… 
Highly Cited
1990
Highly Cited
1990
Thrombin generation is not increased in the blood of hemophilia B patients after the infusion of a purified factor IX concentrate.
Prothrombin complex concentrates (PCC), licensed for the treatment of hemophilia B, are known to carry a significant risk of… 
1980
1980
Increased Fibrinopeptide A after Prothrombin Complex Concentrates
Summary Prothrombin complex concentrates (PCC) are known to carry a risk of thromboembolism. We have chosen to reassess the… 
1978
1978
Use of prothrombin complex concentrates in hemophiliacs with inhibitors: clinical and laboratory studies.
Nine patients with severe classic hemophilia and inhibitors against factor VIII were treated for 156 bleeding episodes with 503… 
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