prothrombin complex concentrates

Known as: PPSB, cofact, factor IX concentrate 
 
National Institutes of Health

Related topics

Related topics

9 relations
ANTI-INHIBITOR COAGULANT COMPLEXfactor IX complex

Broader (2)

Blood Coagulation Factorprothrombin complex

Narrower (5)

KonyneOctaplexProplexProthrombinex
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Papers overview

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Highly Cited
2014
Highly Cited
2014
Comparison of three-factor and four-factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers.
BACKGROUND Four-factor prothrombin complex concentrates (PCCs), which contain factor II, FVII, FIX, and FX, have shown the… (More)
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Highly Cited
2012
Highly Cited
2012
Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model.
BACKGROUND One limitation of the direct thrombin inhibitor dabigatran is the lack of specific antidotes that allow acute bleeding… (More)
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2012
2012
Thromboembolic safety and efficacy of prothrombin complex concentrates in the emergency reversal of warfarin coagulopathy.
BACKGROUND There is uncertainty regarding the efficacy and incidence of thromboembolic events in patients treated with… (More)
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2011
2011
Using prothrombin complex concentrates to rapidly reverse oral anticoagulant effects.
Warfarin is a commonly prescribed anticoagulant that may, in selected situations, require rapid reversal of its effects. Several… (More)
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Highly Cited
2010
Highly Cited
2010
Comparison of fresh frozen plasma and prothrombin complex concentrate for the reversal of oral anticoagulants in patients undergoing cardiopulmonary bypass surgery: a randomized study.
BACKGROUND Fresh frozen plasma (FFP) and prothrombin complex concentrates (PCC) reverse oral anticoagulants. We compared PCC and… (More)
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2008
2008
Biochemical comparison of seven commercially available prothrombin complex concentrates.
AIMS A number of prothrombin complex concentrates (PCCs) are commercially available but they differ in terms of composition. We… (More)
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Highly Cited
2007
Highly Cited
2007
Prothrombin complex concentrate (Octaplex) in patients requiring immediate reversal of oral anticoagulation.
INTRODUCTION Rapid reversal of anticoagulant effect from the use of vitamin K antagonists (VKA) is essential when acute bleeding… (More)
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2004
2004
Identification of prothrombin as a major thrombogenic agent in prothrombin complex concentrates.
Prothrombin complex concentrates (PCC) were compared in an in vitro test system for thrombogenicity (thrombin generation assay… (More)
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Review
1999
Review
1999
Use of prothrombin complex concentrates and activated prothrombin complex concentrates as prophylactic therapy in haemophilia patients with inhibitors.
Haemophilia patients with inhibitors are treated for acute bleeding with prothrombin complex concentrates (PCCs) or activated… (More)
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1999
1999
Influence of prothrombin complex concentrates on plasma coagulation in critically ill patients
Objective: To evaluate thrombogenicity of prothrombin complex concentrates (PCCs) in critically ill patients.¶Design: Prospective… (More)
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