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protein phosphatase 2B binding

Known as: calcineurin binding 
Interacting selectively and non-covalently with the enzyme protein phosphatase 2B. [GOC:jl]
National Institutes of Health

Papers overview

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2020
2020
Altering of host larval (Spodoptera exigua) calcineurin activity in response to ascovirus infection.
BACKGROUND Calcineurin is involved in numerous of cellular processes and Ca2+-dependent signal transduction pathways. With… 
2016
2016
Tacrolimus restores podocyte injury and stabilizes the expression of Cabin1 in 5/6 nephrectomized rats
Abstract Podocyte injury is a vital factor, which induces massive proteinuria. Studies have shown that tacrolimus (TAC) protected… 
2014
2014
Direct Evidence for Calcineurin Binding to the Exon-7 Loop of the Sodium-Bicarbonate Cotransporter NBCn1
The NaHCO3 cotransporter NBCn1 plays a role in neutralizing intracellular acid loads at the basolateral membrane in cells of the… 
2009
2009
Calcineurin regulates phosphorylation status of transcription factor osterix.
Highly Cited
2002
Highly Cited
2002
A potential role for nuclear factor of activated T-cells in receptor tyrosine kinase and G-protein-coupled receptor agonist-induced cell proliferation.
We have studied the role of nuclear factor of activated T-cells (NFAT) transcription factors in the induction of vascular smooth… 
2001
2001
The methods and compositions relating to a muscle-specific sarcomeric calcineurin binding protein (Karusarushin)
本発明は、カルシニューリン関連タンパク質（カルサルシン）として知られるポリペプチドに関する。 カルサルシン−１、−２、および−３は、カルシニューリン、テレトニン、およびα−アクチニンに結合し、これはこれらの分子と筋節との間での連結を提供する。 筋節の機能不全は最終的には、カルシニューリンの活性化を生じ、そして結果として肥大性心筋症を生じる。 従って、これらの医学的状態に関してカルサルシンを利用する方法が本明細書中で提供され、そしてこの方法は、カルサルシンと相互作用するペプチドをスクリーニングする工程、カルシニューリンまたはα−アクチニンへのカルサルシンの結合のモジュレーターをルクリーニングする工程を包含する。 カルシニューリン活性を調節するための方法、遺伝子の転写のカルシニューリン活性化を阻害するための方法、ならびに心肥大、心不全、およびＩＩ型糖尿病を処置するための方法が提供される。 
1997
1997
Determinants of calcineurin binding to model membranes.
The biochemical factors that lead to membrane targeting of the Ser/Thr protein phosphatase calcineurin were examined using model… 
1997
1997
Molecular Interactions of Cyclosporin A with P-glycoprotein
The interaction between P-glycoprotein (140-180 kDa) from the multidrug-resistant Chinese hamster ovary cell line CHRC5 and… 
1995
1995
Mutations That Perturb Cyclophilin A Ligand Binding Pocket Confer Cyclosporin A Resistance in Saccharomycescerevisiae(*)
In complex with the peptidyl-prolyl isomerase cyclophilin A, the immunosuppressive antifungal drug cyclosporin A (CsA) inhibits a… 
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