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protein kinase C iota

Known as: Atypical protein kinase C iota, PKC iota, protein kinase C-iota 
National Institutes of Health

Related topics

Related topics

2 relations
PRKCI gene

Broader (1)

protein kinase C lambda

Papers overview

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2012
2012
Abstract 446: Protein kinase Ciota is a new prognostic factor in gastric cancer
Background: Protein kinase Ciota (PKCiota) have been reported to be an important effector of oncogenic K-ras. Furthermore… 
2009
2009
Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1)
Protein kinase Cι (PKCι) is activated by oncogenic Ras proteins and is required for K-Ras–induced transformation and colonic… 
2009
2009
Rescue of atypical protein kinase C in epithelia by the cytoskeleton and Hsp70 family chaperones
Atypical PKC (PKCι) is a key organizer of cellular asymmetry. Sequential extractions of intestinal cells showed a pool of… 
Highly Cited
2008
Highly Cited
2008
Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.
Highly Cited
2008
Highly Cited
2008
Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota.
K-Ras mutations are frequently found in various cancers and are associated with resistance to treatment or poor prognosis… 
2004
2004
Regulation of Interleukin Receptor-associated Kinase (IRAK) Phosphorylation and Signaling by Iota Protein Kinase C*
We have previously shown that the activity of the interleukin-1 (IL-1) receptor-associated kinase (IRAK) is required for nerve… 
2004
2004
Bcr-Abl regulates protein kinase Ciota (PKCiota) transcription via an Elk1 site in the PKCiota promoter.
The protein kinase C (PKC) family of serine/threonine kinases plays an important role in numerous cancer signaling pathways… 
Highly Cited
2001
Highly Cited
2001
Nerve growth factor stimulates the interaction of ZIP/p62 with atypical protein kinase C and targets endosomal localization: Evidence for regulation of nerve growth factor‐induced differentiation
Atypical protein kinase Cs zeta and lambda/iota play a functional role in the regulation of NGF‐induced differentiation and… 
Highly Cited
1999
Highly Cited
1999
Expression and translocation of protein kinase C isoforms in rat microglial and astroglial cultures
Cellular distribution and activation by phorbol myristate acetate (PMA) of classical (α, βI, βII,γ), novel (δ, ϵ, θ, η), and… 
1983
1983
Desulfated carrageenans and cytotoxicity of human monocytes
AbstractCarrageenan is a high molecular weight sulfated polygalactose extracted from the marine algae Chondrus cripsus and has… 
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