protein alkylation

Known as: protein amino acid alkylation 
The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom. [GOC:ma]
National Institutes of Health

Papers overview

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2013
2013
Acrolein, a reactive aldehyde found in cigarette smoke, is thought to induce its biological effects primarily by irreversible… (More)
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2012
2012
Alkylation of cysteine residues has been used extensively for characterization of proteins and their mode of action in biological… (More)
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2006
2006
A new protein modification reaction has been developed based on a palladium-catalyzed allylic alkylation of tyrosine residues… (More)
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2003
2003
A tyrosinase-directed therapeutic approach for malignant melanoma therapy uses the depigmenting phenolic agents such as 4… (More)
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1997
1997
Several alkylphenols (e.g., 2,6-di-tert-butyl-4-methylphenol, BHT) form reactive quinone methide intermediates (e.g., 2,6-di-tert… (More)
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Highly Cited
1996
Highly Cited
1996
Transcriptional activation of heat shock protein genes is a common response to proteotoxic stress. Many drugs and chemicals that… (More)
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1994
1994
The formation of carbon centered free radicals, identified as methylcarbonyl species, was observed using ESR spectroscopy and the… (More)
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1992
1992
Ronidazole protein-bound adducts were generated by the in vitro anaerobic incubation of [2-methylene-14C]ronidazole with… (More)
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1982
1982
Ronidazole (1-methyl-5-nitroimidazole-2-methanol carbamate) is reductively metabolized by liver microsomal and purified NADPH… (More)
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