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protein alkylation
Known as:
protein amino acid alkylation
The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom. [GOC:ma]
National Institutes of Health
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2016
2016
6-Hydroxydopamine Inhibits the Hepatitis C Virus through Alkylation of Host and Viral Proteins and the Induction of Oxidative Stress.
Matthew A. Lafrenière
,
Megan H. Powdrill
,
R. Singaravelu
,
J. Pezacki
ACS Infectious Diseases
2016
Corpus ID: 24625377
Many viruses, including the hepatitis C virus (HCV), are dependent on the host RNA silencing pathway for replication. In this…
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Review
2014
Review
2014
A journey through PROTEOSONICS.
J. E. Araújo
,
E. Oliveira
,
+4 authors
J. Capelo
Talanta: The International Journal of Pure and…
2014
Corpus ID: 8041078
2013
2013
Protein alkylation by the α,β‐unsaturated aldehyde acrolein. A reversible mechanism of electrophile signaling?
M. J. Randall
,
Milena Hristova
,
A. van der Vliet
FEBS Letters
2013
Corpus ID: 207728760
2012
2012
Selectivity of labeled bromoethylamine for protein alkylation
Simona Marincean
,
Montserrat Rabago Smith
,
L. Beltz
,
B. Borhan
Journal of Molecular Modeling
2012
Corpus ID: 45506975
Alkylation of cysteine residues has been used extensively for characterization of proteins and their mode of action in biological…
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2007
2007
Simplifying sample handling for protein identification by peptide mass fingerprint using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
F. Cordeiro
,
R. Carreira
,
R. Rial-Otero
,
M. G. Rivas
,
I. Moura
,
J. Capelo
Rapid Communications in Mass Spectrometry
2007
Corpus ID: 8586917
An ultrasonic bath, an ultrasonic probe and a sonoreactor were used to speed up the kinetics of the reactions involved in each…
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2005
2005
Mass spectrometric investigation of protein alkylation by the RNA footprinting probe kethoxal.
O. Akinsiku
,
E. Yu
,
D. Fabris
Journal of Mass Spectrometry
2005
Corpus ID: 24190399
The reactivity of the RNA footprinting reagent kethoxal (KT) toward proteins was investigated by electrospray ionization-Fourier…
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2001
2001
Comparative metabolism, covalent binding and toxicity of BHT congeners in rat liver slices.
M. Reed
,
H. Fujiwara
,
D. Thompson
Chemico-Biological Interactions
2001
Corpus ID: 41330113
1997
1997
Immunochemical visualization and identification of rat liver proteins adducted by 2,6-di-tert-butyl-4-methylphenol (BHT).
M. Reed
,
D. Thompson
Chemical Research in Toxicology
1997
Corpus ID: 22583433
Several alkylphenols (e.g., 2,6-di-tert-butyl-4-methylphenol, BHT) form reactive quinone methide intermediates (e.g., 2,6-di-tert…
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1992
1992
Modulation of trenimon-induced cytotoxicity by DT-diaphorase in isolated rat hepatocytes under aerobic versus hypoxic conditions.
J. Silva
,
D. N. Rao
,
P. O'Brien
Cancer Research
1992
Corpus ID: 14702575
Trenimon belongs to a class of aziridinylbenzoquinone anticancer drugs that cross the blood-brain barrier. In this study we have…
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1991
1991
The use of 19F NMR in the study of protein alkylation by fluorinated reactive intermediates.
J. Harris
,
M. W. Anders
Advances in Experimental Medicine and Biology
1991
Corpus ID: 23346732
Cysteine S-conjugates are formed as a result of enzymatic conjugation of xenobiotics with the tripeptide glutathione and…
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