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protein TDP-43
Known as:
TAR DNA-Binding Protein 43
, TDP-43
TAR DNA-binding protein 43 (414 aa, ~45 kDa) is encoded by the human TARDBP gene. This protein is involved in the regulation of both transcription…
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National Institutes of Health
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Related topics
Related topics
5 relations
Genes, Regulator
RNA Splicing
TARDBP gene
TARDBP wt Allele
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Atomic Structures of Segments within the Low Comlpexity Domain of TDP-43 Offer Insight into its Dual Functions of Reversible and Pathogenic Aggregation
E. L. Guenther
,
Q. Cao
,
+6 authors
D. Eisenberg
2018
Corpus ID: 216892630
2018
2018
TDP-43 shapeshifts to encipher FTD severity TDP-43 forms cytoplasmic aggregates in degenerating neurons of frontotemporal dementia ( FTD ) patients
2018
Corpus ID: 111383147
Amyotrophic lateral sclerosis (ALS) and FTD, a type of frontotemporal lobar degeneration (FTLD), are devastating and fatal…
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2017
2017
Systems Biology in the Context of Aging and Disease
J. Caruthers
2017
Corpus ID: 26913421
Oral Presentations 9:00 11:30am JSCBB A104 Development of Bivalent Inhibitors Targeting the Interaction of HIV and the Co…
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2016
2016
Molecular Dynamics Simulations Mechanisms of Membrane Pore Formation by Amyloidogenic Peptides in Amyotrophic Lateral Sclerosis
Charles H. Chen
,
A. Khan
,
Joseph Jen‐Tse Huang
,
M. Ulmschneider
2016
Corpus ID: 40621231
Using unbiased atomic-detailed molecular dynamics simulations, the C-terminal fragments of TDP-43 are observed to aggregate and…
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Review
2011
Review
2011
Redox signaling directly regulates TDP-43 via cysteine oxidation and disulfide cross-linking
T. Cohen
,
Andrew W. Hwang
,
Travis L. Unger
,
J. Trojanowski
,
V. Lee
2011
Corpus ID: 5625361
Review timeline: Submission date: 10 February 2011 Editorial Decision: 02 March 2011 Additional correspondence (author): 03 March…
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2010
2010
Aggregation party in ALS
L. Osherovich
2010
Corpus ID: 72093807
A University of Pennsylvania team has used a yeast screening technology from FoldRx to show that the amyotrophic lateral…
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Review
2009
Review
2009
Sporadic inclusion body myositis , myonuclei , and TDP-43
S. Greenberg
2009
Corpus ID: 49234059
Current Opinion in Neurology 2009, 22:516–523 Purpose of review Recent developments pertaining to disease mechanisms in the…
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