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TARDBP gene

Known as: TARDBP, TAR DNA-BINDING PROTEIN, 43-KD, TAR DNA binding protein 
This gene is involved in transcription and mRNA splicing.
National Institutes of Health

Related topics

Related topics

6 relations
AMYOTROPHIC LATERAL SCLEROSIS 10 (disorder)RNA SplicingTranscriptional Regulationprotein TDP-43

Broader (1)

Genes

Narrower (1)

TARDBP wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Hu Antigen R (HuR) Is a Positive Regulator of the RNA-binding Proteins TDP-43 and FUS/TLS
Background: RNA processing abnormalities have been linked to amyotrophic lateral sclerosis (ALS). Results: HuR promotes the… 
Review
2014
Review
2014
Extensive molecular genetic survey of Taiwanese patients with amyotrophic lateral sclerosis
Highly Cited
2012
Highly Cited
2012
TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans
TDP-43 is a multifunctional nucleic acid binding protein linked to several neurodegenerative diseases including Amyotrophic… 
2012
2012
Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese
2012
2012
Identification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines
Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein… 
2012
2012
Novel TARDBP mutations in Nordic ALS patients
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative syndrome primarily affecting the upper and lower motor neurons. A… 
Highly Cited
2011
Highly Cited
2011
Molecular Dissection of TDP-43 Proteinopathies
TDP-43 has been identified as a major component of ubiquitin-positive tau-negative cytoplasmic inclusions in frontotemporal lobar… 
2010
2010
Enlarging clinical spectrum of FALS with TARDBP gene mutations: S393L variant in an Italian family showing phenotypic variability and relevance for genetic counselling
Objective: The present study was aimed to enlarge the Italian ALS sample analysed for TARDBP gene mutations. Methods: Genomic DNA… 
2009
2009
No association of TDP-43 with sporadic frontotemporal dementia
2009
2009
Genetic variants in the promoter of TARDBP in sporadic amyotrophic lateral sclerosis
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