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TARDBP gene

Known as: TARDBP, TAR DNA-BINDING PROTEIN, 43-KD, TAR DNA binding protein 
This gene is involved in transcription and mRNA splicing.
National Institutes of Health

Related topics

Related topics

6 relations
AMYOTROPHIC LATERAL SCLEROSIS 10 (disorder)RNA SplicingTranscriptional Regulationprotein TDP-43

Broader (1)

Genes

Narrower (1)

TARDBP wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Modelling FUS Mislocalisation in an In Vitro Model of Innervated Human Muscle
Degeneration of distal axons and neuromuscular junctions is an early feature in the pathology of amyotrophic lateral sclerosis… 
2016
2016
Folliculin, a tumor suppressor associated with Birt-Hogg-Dubé (BHD) syndrome, is a novel modifier of TDP-43 cytoplasmic translocation and aggregation.
TDP-43 was identified as the major component of ubiquitin and autophagosome-positive cytoplasmic inclusions in neurons in the… 
2016
2016
Untangling the structure of the TDP‐43 N‐terminal domain
Neurodegenerative diseases are fast becoming a major health issue in aging societies. According to the World Health Organization… 
2014
2014
Adenoviral expression of TDP‐43 and FUS genes and shRNAs for protein degradation pathways in rodent motoneurons in vitro and in vivo
Formation of cytoplasmic aggregates in neuronal and glial cells is one of the pathological hallmarks of amyotrophic lateral… 
2012
2012
Identification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines
Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein… 
2012
2012
Co-occurrence of progressive anarthria with an S393L TARDBP mutation and ALS within a family
Summary Progressive anarthria is usually classified as a tau pathology. We report an 87-year-old female with a family history of… 
2012
2012
TARDBP mutations are not a frequent cause of ALS in Finnish patients
In previous studies 1-3 % of ALS patients have TARDBP mutations as the cause of the disease. TARDBP mutations have been reported… 
2012
2012
Classification of familial amyotrophic lateral sclerosis by family history: effects on frequency of genes mutation
Objective To classify familial amyotrophic lateral sclerosis (FALS) on the base of family history, and to determine whether… 
2011
2011
PRO-MINE: A Bioinformatics Repository and Analytical Tool for TARDBP Mutations
TDP‐43 is a multifunctional RNA‐binding protein found to be a major protein component of intracellular inclusions found in… 
Review
2010
Review
2010
[Research in amyotrophic lateral sclerosis: what is new in 2009?].
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