Skip to search formSkip to main contentSkip to account menu

TARDBP wt Allele

Known as: TDP-43, ALS10, TDP43 
Human TARDBP wild-type allele is located in the vicinity of 1p36.22 and is approximately 13 kb in length. This allele, which encodes TAR DNA-binding… 
National Institutes of Health

Related topics

Related topics

4 relations
RNA SplicingTranscriptional Regulationprotein TDP-43

Broader (1)

TARDBP gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Temporal Variant Frontotemporal Dementia Is Associated with Globular Glial Tauopathy
Supplemental Digital Content is available in the text. 
Highly Cited
2011
Highly Cited
2011
Molecular Dissection of TDP-43 Proteinopathies
TDP-43 has been identified as a major component of ubiquitin-positive tau-negative cytoplasmic inclusions in frontotemporal lobar… 
Highly Cited
2010
Highly Cited
2010
A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of upper and lower… 
Review
2010
Review
2010
State of the art and the dark side of amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is a disorder that involves the degeneration of motor neurons, muscle atrophy, and paralysis… 
2010
2010
A new actor on the frontotemporal lobar degeneration stage
Neurology 2010;74:354–356 Following hard on the heels of discoveries of pathogenic mutations in the TAR DNA-binding protein 43… 
Highly Cited
2009
Highly Cited
2009
TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases
2009
2009
No association of TDP-43 with sporadic frontotemporal dementia
2007
2007
TDP-43 gene analysis in frontotemporal lobar degeneration
2007
2007
Evidence That TDP-43 is Not the Major Ubiquitinated Target Within the Pathological Inclusions of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the presence of various types of… 
Review
2007
Review
2007
The complex aetiology of frontotemporal lobar degeneration
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)