TARDBP wt Allele

Known as: TDP-43, ALS10, TDP43 
Human TARDBP wild-type allele is located in the vicinity of 1p36.22 and is approximately 13 kb in length. This allele, which encodes TAR DNA-binding… (More)

Topic mentions per year

Topic mentions per year

2001-2018
02040608020012018

Papers overview

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Review
2016
Review
2016
Frontotemporal dementia is a devastating neurodegenerative disease causing stark alterations in personality and language… (More)
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Highly Cited
2011
Highly Cited
2011
We used cross-linking and immunoprecipitation coupled with high-throughput sequencing to identify binding sites in 6,304 genes as… (More)
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Highly Cited
2010
Highly Cited
2010
TDP-43 has been found in inclusion bodies of multiple neurological disorders, including amyotrophic lateral sclerosis… (More)
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Highly Cited
2008
Highly Cited
2008
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disorder characterized pathologically by ubiquitinated TAR DNA… (More)
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Highly Cited
2008
Highly Cited
2008
Recently, TDP-43 was identified as a key component of ubiquitinated aggregates in amyotrophic lateral sclerosis (ALS), an adult… (More)
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Highly Cited
2008
Highly Cited
2008
To identify novel causes of familial neurodegenerative diseases, we extended our previous studies of TAR DNA-binding protein 43… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND TDP-43 is a major component of the ubiquitinated inclusions that characterise amyotrophic lateral sclerosis (ALS) and… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Amyotrophic lateral sclerosis (ALS) is a common, fatal motor neuron disorder with no effective treatment. Approximately… (More)
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Highly Cited
2006
Highly Cited
2006
Ubiquitin-positive, tau- and alpha-synuclein-negative inclusions are hallmarks of frontotemporal lobar degeneration with… (More)
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Highly Cited
2006
Highly Cited
2006
Ubiquitin-positive tau-negative neuronal cytoplasmic inclusions and dystrophic neurites are common pathological features in… (More)
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