Skip to search formSkip to main contentSkip to account menu

TARDBP wt Allele

Known as: TDP-43, ALS10, TDP43 
Human TARDBP wild-type allele is located in the vicinity of 1p36.22 and is approximately 13 kb in length. This allele, which encodes TAR DNA-binding… 
National Institutes of Health

Related topics

Related topics

4 relations
RNA SplicingTranscriptional Regulationprotein TDP-43

Broader (1)

TARDBP gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Neuroplasticity of the dendritic spine : early dysfunction in amyotrophic lateral sclerosis
Neurodegenerative diseases are heterogeneous disorders that share common features of progression, whereby vulnerable cortical… 
2018
2018
The Effect of Single and Double Acetylation of Lysine Residues on Structural and Dynamical Features of Human Splicing Factor TDP-43 - A Statistical Ensemble Analysis.
BACKGROUND The acetylated inclusions containing TDP-43 are found in the spinal cord of amyotrophic lateral sclerosis (ALS… 
2017
2017
Analysis of the role of TDP-43 and its binding partners in neurodegenerative diseases
2017
2017
INVESTIGATING MODIFIERS OF ALS TOXICITY THROUGH A GENOME WIDE RNAI SCREEN OF C . ELEGANS
INTRODUCTION Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease, afflicts over 400,000 people worldwide… 
2016
2016
Expression of TDP 43 in cervical cancer
TDP43 is ubiquitously expressed in human tissues and plays a crucial role in a wide range of neurodegenerative diseases. However… 
Review
2015
Review
2015
[RNA processing TDP-43 protein has a main pathological role in FTLD and ALS].
TDP-43 is mainly a nuclear protein belonging to the heterogeneous ribonucleoproteins family. It plays a crucial role in the… 
2012
2012
TAR DNA binding protein-43 and fused in sarcoma/translocated in liposarcoma protein in two neurodegenerative diseases.
: TAR DNA binding protein-43(TDP-43) and fused in sarcoma/translocated in liposarcoma protein (FUS/TLS) have been found to be… 
2010
2010
The basis of VCP-mediated degeneration: Insights from a Drosophila model of disease
Valosin-containing protein (VCP) is a highly conserved molecular chaperone that regulates a wide array of essential cellular… 
2010
2010
PONM17 Augmentation of the heat shock response in an in vitro model of sporadic inclusion body myositis
Sporadic inclusion body myositis (IBM), the commonest myopathy acquired by those aged over 50 years, remains without proven… 
2009
2009
Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains : their relation to AD common pathology