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prostaglandin-F synthase activity

Known as: NADPH-dependent prostaglandin D2 11-keto reductase activity, PGF2alpha synthetase activity, prostaglandin F synthase activity 
Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

prostaglandin metabolic process

Papers overview

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Highly Cited
2003
Highly Cited
2003
Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma.
BACKGROUND Regulation of prostaglandin synthesis and the activation of human airway fibroblasts associated with the remodeling of… 
Highly Cited
2002
Highly Cited
2002
Age‐related loss of extrastriatal dopamine D2‐like receptors in women
Positron emission tomography (PET) studies have indicated that the in vivo availability of dopamine D2‐like receptors declines… 
Highly Cited
2002
Highly Cited
2002
Control of Prostaglandin Stereochemistry at the 15-Carbon by Cyclooxygenases-1 and -2
Prostaglandin synthesis by cyclooxygenases-1 and -2 (COX-1 and COX-2) involves an initial oxygenation of arachidonic acid at C-11… 
Highly Cited
1998
Highly Cited
1998
Structural Characterization of Arachidonyl Radicals Formed by Prostaglandin H Synthase-2 and Prostaglandin H Synthase-1 Reconstituted with Mangano Protoporphyrin IX*
A tyrosyl radical generated in the peroxidase cycle of prostaglandin H synthase-1 (PGHS-1) can serve as the initial oxidant for… 
Highly Cited
1988
Highly Cited
1988
AH6809, a prostaglandin DP‐receptor blocking drug on human platelets
1 The effect of AH6809 (6‐isopropoxy‐9‐oxoxanthene‐2‐carboxylic acid) has been studied upon the antiaggregatory and aggregatory… 
1982
1982
Prostaglandin formation in man during intake of different amounts of linoleic acid in formula diets.
Prostaglandin formation in healthy female volunteers was investigated during intake of different amounts of linoleic acid in… 
1979
1979
Independence of the cyclic AMP-lowering activity of thromboxane A2 from the platelet release reaction.
Highly Cited
1973
Highly Cited
1973
The effect of chronic sodium loading and sodium restriction on plasma prostaglandin A, E, and F concentrations in normal humans.
It has been suggested that prostaglandins may be involved in the control of sodium homeostasis. Prostaglandin A and prostaglandin… 
1972
1972
Partial purification and properties of cat plasma prostaglandin A isomerase.
Highly Cited
1970
Highly Cited
1970
Sex expression in cucumber plants as affected by 2-chloroethylphosphonic Acid, ethylene, and growth regulators.
The effects of 2-chloroethylphosphonic acid (Ethrel), ethylene, and some growth retardants on sex expression of cucumber plants… 
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