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prostaglandin-E2 9-reductase activity

Known as: PGE2-9-ketoreductase activity, 9-keto-prostaglandin E2 reductase activity, reductase, 15-hydroxy-9-oxoprostaglandin 
Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9… 
National Institutes of Health

Papers overview

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2009
2009
Characterization of covalent adducts of nucleosides and DNA formed by reaction with levuglandin.
Enhanced expression of cyclooxygenase-2 (COX-2) is associated with development of several cancers. The product of COX-2… 
2006
2006
Prostaglandin E2 binding and cyclic AMP production in isolated bone cells
SummaryThe binding of prostaglandin E2 (PGE2) to bone cells was studied to provide direct evidence for the existence of specific… 
2004
2004
Characterization of bis(levuglandinyl) urea derivatives as products of the reaction between prostaglandin H2 and arginine.
Levuglandins are gamma-keto aldehydes formed by rearrangement of prostaglandin (PG) H(2) in aqueous solution. Levuglandins are… 
1986
1986
Alteration of prostanoid metabolism in rats with magnesium deficiency.
1983
1983
Substrate specificity of three prostaglandin dehydrogenases.
1982
1982
Cutaneous erythema and blood pressure lowering effects of topically applied 16-vinylprostaglandins.
1981
1981
Glutathione-related inhibition of prostaglandin metabolism.
1980
1980
Prostaglandins and prostaglandin metabolites in human gastric juice.
1977
1977
High-performance liquid chromatography of p-nitrophenacyl esters of selected prostaglandins on silver ion- loaded microparticulate cation-exchange resin.
1973
1973
Prostaglandins. A total synthesis of (plus or minus)-11,15-dideoxy-PGE2 and (plus or minus)-11-deoxy-PGE2 methyl ester.
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