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propylnitrosourea

Known as: 1-propyl-1-nitrosourea, N-nitroso-N-propylurea, N-propyl-N-nitrosourea 
National Institutes of Health

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3 relations

Broader (3)

CarcinogensMutagensNitrosourea Compounds

Papers overview

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1997
1997
Deviated overexpression of TCR-beta, TCR-gamma, CD4, and CD8 on thymic lymphomas induced by 1-propyl-1-nitrosourea: destruction of the allelic exclusion of TCR-beta and expression of functional TCR…
Thymic lymphomas (FTLs) induced by the chemical carcinogen 1-propyl-1-nitrosourea (PNU) in F344 rats showed deviated… 
1986
1986
Role of the thymus in propylnitrosourea-induced thymic lymphomagenesis in F344 rats.
The role of the thymus in propylnitrosourea (PNU)-induced thymic lymphomagenesis was studied in F344 rats with genetically… 
1985
1985
Genetically determined susceptibility of Fischer 344 rats to propylnitrosourea-induced thymic lymphomas.
Administration of propylnitrosourea p.o. by our protocol induced a high incidence of hematolymphatic neoplasms in all six rat… 
1983
1983
Synthesis and anticonvulsive activity of a N-propylurea-ninhydrin condensation product in mice.
1982
1982
Distribution and metabolism of 1-propyl-1-nitrosourea in rats.
The carcinogen 1-[14C]propyl-1-nitrosourea (PNU) was readily absorbed from the rat gut, and the radioactivity was excreted mainly… 
1982
1982
Vascular tumors of the spleen and other neoplasms induced in Syrian golden hamsters by 1-propyl-1-nitrosourea.
Continuous administration of either 400 ppm or 100 ppm 1-propyl-1-nitrosourea (PNU) in drinking water to Syrian golden hamsters… 
1980
1980
Induction of duodenal-tumors and thymomas in Fischer rats by continuous oral administration of 1-propyl-1-nitrosourea.
Male and female F344/DuCrj rats were given 400 ppm solution of 1-propyl-1-nitrosourea continuously in their drinking water. The… 
1976
1976
Induction of tumors in female Donryu rats by a single administration of 1-propyl-1-nitrosourea.
Three groups of female Donryu rats were given a single gastric intubation of 800, 400, or 200 mg/kg body weight of 1-propyl-1… 
1970
1970
Some aspects of the mechanism of action of 1-propyl-1-nitrosourea.
1962
1962
Hypoglycæmic Activity of N-Benzenesulphonyl-N′-iso-propylurea and N-Benzenesulphonyl-N′-n-butylurea in Experimental Animals
HYPOGLYCÆMIC activity of sulphonylureas is now well recognized. In a search for more effective compounds we have synthesized a… 
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