propyl-N'-nitro-N-nitrosoguanidine

The unscheduled DNA synthesis (UDS) assay measures DNA repair following in vitro treatment of rat primary hepatocytes. This… (More)

To determine the influence of excision repair on the distribution of N-propyl-N'-nitro-N-nitrosoguanidine (PNNG)-induced mutation… (More)

The mutational specificity of the monofunctional alkylating agent N-propyl-N'-nitro-N-nitrosoguanidine (PNNG) has been determined… (More)

N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and N-propyl-N'-nitro-N-nitrosoguanidine (PNNG) were administered to male F344 rats… (More)

Sequential studies were made on the histopathologic changes in the glandular stomach of rats induced by a weak carcinogen, N… (More)

To elucidate the developmental process of the intestinal metaplasia of the stomach, PNNG was orally administered to dogs and the… (More)

PNNG, the propyl derivative of MNNG, was administered to Wistar rats at a concentration of 59.5 μg/ml in the drinking water for 4… (More)

For men with urethral discharge, a simple gram stained smear is 98% sensitive and over 99% specific in detecting gonococcal… (More)

N-methyl-(MNNG), N-ethyl-(ENNG), and N-propyl-(PNNG) derivatives of N'-nitro-N-nitrosoguanidine inhibited the growth of… (More)

formation of the active alkylating species, i.e., the alkyldiazonium ion, has been described by Shapiro (3), and the alkylation… (More)