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propoxyphene napsylate

Known as: 2-Naphthalenesulfonic acid, compd. with (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)p- ropyl propanoate (1:1), napsylate propoxyphene, propoxyphene napsylate [Chemical/Ingredient] 
A synthetic diphenyl propionate derivative structurally related to methadone, Propoxyphene Napsylate acts as a central narcotic and analgesic agent… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
PurposeApproximately 50% of active pharmaceutical ingredients (APIs) are manufactured and formulated as salts, due to their… Expand
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Highly Cited
2004
Highly Cited
2004
Twelve subjects (3 male) took part in a randomised double-blind four way crossover study designed to examine the cognitive and… Expand
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2004
2004
Propoxyphene and its major metabolite norpropoxyphene have been determined in blood and liver in 29 cases of death in which… Expand
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1994
1994
Summary264 patients experiencing pain related to osteoarthritis of the hip and/or knee were enrolled in a double-blind randomised… Expand
1987
1987
We compared naproxen sodium (550 mg) and propoxyphene napsylate with acetaminophen (PN/A, 100 mg with 650 mg) for pain relief… Expand
1977
1977
The maximum doses of propoxyphene napsylate used to treat heroin addicts produce a degree of morphine-like activity equal to that… Expand
1975
1975
A sensitive and specific GLC assay method was developed for the determination of propoxyphene, its major metabolite… Expand
Highly Cited
1975
Highly Cited
1975
Propoxyphene napsylate and methadone hydrochloride were each administered under double-blind conditions to 36 outpatients for 21… Expand
Highly Cited
1971
Highly Cited
1971
Abstract Propoxyphene hydrochloride was administered po, im, and iv to normal human volunteers. Included in the cross-over study… Expand
1971
1971
Abstract The acute toxicity of oral and parenteral doses of propoxyphene HCl was studied in laboratory animals. Large iv, im, or… Expand