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propoxyphene napsylate

Known as: 2-Naphthalenesulfonic acid, compd. with (S-(R*,S*))-3-(dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)p- ropyl propanoate (1:1), napsylate propoxyphene, propoxyphene napsylate [Chemical/Ingredient] 
A synthetic diphenyl propionate derivative structurally related to methadone, Propoxyphene Napsylate acts as a central narcotic and analgesic agent… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
PurposeApproximately 50% of active pharmaceutical ingredients (APIs) are manufactured and formulated as salts, due to their… Expand
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Highly Cited
1995
Highly Cited
1995
Twelve subjects (3 male) took part in a randomised double-blind four way crossover study designed to examine the cognitive and… Expand
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1994
1994
Summary264 patients experiencing pain related to osteoarthritis of the hip and/or knee were enrolled in a double-blind randomised… Expand
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1987
1987
We compared naproxen sodium (550 mg) and propoxyphene napsylate with acetaminophen (PN/A, 100 mg with 650 mg) for pain relief… Expand
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Highly Cited
1984
Highly Cited
1984
In a study of 160 patients (including 114 active heroin addicts and 42 former heroin addicts maintained on methadone… Expand
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1977
1977
The maximum doses of propoxyphene napsylate used to treat heroin addicts produce a degree of morphine-like activity equal to that… Expand
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1975
1975
Propoxyphene and its major metabolite norpropoxyphene have been determined in blood and liver in 29 cases of death in which… Expand
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1975
1975
A sensitive and specific GLC assay method was developed for the determination of propoxyphene, its major metabolite… Expand
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1975
1975
Propoxyphene napsylate and methadone hydrochloride were each administered under double-blind conditions to 36 outpatients for 21… Expand
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1971
1971
Abstract Propoxyphene napsylate was studied in reproduction and teratology experiments in rats and in a teratology experiment in… Expand
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