progesterone metabolic process

Known as: progesterone metabolism 
The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for… (More)
National Institutes of Health

Papers overview

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2007
2007
Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility
Withdrawal from high levels of progesterone in rodents has been proposed as a model for premenstrual syndrome or postpartum… (More)
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Highly Cited
2006
Highly Cited
2006
Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective.
The ovarian hormone progesterone is neuroprotective in different experimental models of neurodegeneration. In the nervous system… (More)
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2006
2006
Timing of neutrophil activation and expression of proinflammatory markers do not support a role for neutrophils in cervical ripening in the mouse.
The mechanisms that facilitate remodeling of the cervix in preparation for and during parturition remain poorly understood. In… (More)
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2005
2005
Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: a potential component of nociception.
A crucial biochemical reaction in vertebrates is progesterone conversion into neuroactive metabolites such as dihydroprogesterone… (More)
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2005
2005
Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors.
OBJECTIVE Hpr6 (heme-1 domain protein/human progesterone receptor) is one of a family of proteins that are implicated in… (More)
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2004
2004
Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma
Recent evidence suggests that progesterone metabolites play important roles in regulating breast cancer. Previous studies have… (More)
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Highly Cited
2003
Highly Cited
2003
Acute reduction in serum progesterone concentrations after feed intake in dairy cows.
This study tested the hypothesis that high feed consumption will acutely decrease circulating progesterone concentrations. In the… (More)
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2003
2003
Seizure exacerbation associated with inhibition of progesterone metabolism.
The reduced progesterone metabolite tetrahydroprogesterone is a potent positive modulator of GABA(A) chloride conductance that… (More)
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1998
1998
Mouse oocytes regulate granulosa cell steroidogenesis throughout follicular development.
Mouse oocytes secrete a factor(s) that inhibits progesterone and enhances estradiol production by granulosa cells. This study… (More)
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1993
1993
Simple extraction and enzyme immunoassays for estrogen and progesterone metabolites in the feces of Macaca fascicularis during non-conceptive and conceptive ovarian cycles.
A simple method for extracting ovarian steroids from feces is presented, together with enzyme immunoassay systems for measuring… (More)
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