FAQ

pro-diazepam

Known as: 2-benzoyl-4-chloromethyl-N-lysyl-glycinanilide, 2-benzoyl-4-chloromethyl-N-lysylglycin anilide, Avizafone 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2016
02419932016

Related topics

Related topics

1 relation

Broader (1)

Dipeptides

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
pro-diazepam
Dipeptides

Papers overview

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2016
2016
Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig.
Current organophosphorus nerve agent medical countermeasures do not directly address the nicotinic effects of poisoning. A series… (More)
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2014
2014
Rapid Delivery of Diazepam from Supersaturated Solutions Prepared Using Prodrug/Enzyme Mixtures: Toward Intranasal Treatment of Seizure Emergencies
Current treatments for seizure emergencies, such as status epilepticus, include intravenous or rectal administration of… (More)
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2008
2008
High-performance liquid chromatography coupled with electrospray tandem mass spectrometry (LC/MS/MS) method for the simultaneous determination of diazepam, atropine and pralidoxime in human plasma.
A high-performance liquid chromatography coupled with electrospray tandem mass spectrometry (LC/MS/MS) procedure for the… (More)
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2006
2006
Efficacy of immediate and subsequent therapies against soman-induced seizures and lethality in rats.
The purpose of the present study was to examine the efficacy of a triple combination of drugs with adequate anticonvulsant… (More)
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2006
2006
Protection against soman-induced neuropathology and respiratory failure: a comparison of the efficacy of diazepam and avizafone in guinea pig.
The purpose of this study was to compare the efficacy of diazepam and the pro-diazepam avizafone in preventing the severity of… (More)
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2003
2003
Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose.
This investigation compared the efficacy of diazepam and the water-soluble prodiazepam-avizafone-in sarin poisoning therapy… (More)
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2000
2000
Stability study of a new antidote drug combination (Atropine-HI-6-Prodiazepam) for treatment of organophosphate poisoning.
The main purpose of this study was to investigate the chemical stability of a new antidote combination for the treatment of… (More)
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2000
2000
Compared efficacy of diazepam or avizafone to prevent soman-induced electroencephalographic disturbances and neuropathology in primates: relationship to plasmatic benzodiazepine pharmacokinetics
We performed an experiment to characterize the toxicity of soman in cynomolgus monkeys in which organophosphorus intoxication was… (More)
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1999
1999
Comparative evaluation of benzodiazepines for control of soman-induced seizures
This study evaluated the ability of six benzodiazepines to stop seizures produced by exposure to the nerve agent soman. Guinea… (More)
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1993
1993
Efficacy of diazepam and avizafone against soman-induced neuropathology in brain of rats.
The purpose of this investigation was to compare the efficacy of diazepam and a water soluble pro-diazepam drug, avizafone (lysyl… (More)
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