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presynaptic active zone

Known as: pre-synaptic active zone 
A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic… 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

pre-synaptic ribbonpresynaptic grid

Broader (1)

presynapse
presynaptic active zone membrane

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Assembly of the presynaptic active zone
Highly Cited
2017
Highly Cited
2017
Bassoon Controls Presynaptic Autophagy through Atg5
Review
2017
Review
2017
Novel Insights into the Physiological Function of the APP (Gene) Family and Its Proteolytic Fragments in Synaptic Plasticity
The amyloid precursor protein (APP) is well known to be involved in the pathophysiology of Alzheimer's disease (AD) via its… 
Highly Cited
2009
Highly Cited
2009
Copy number variation and association analysis of SHANK3 as a candidate gene for autism in the IMGSAC collection
SHANK3 is located on chromosome 22q13.3 and encodes a scaffold protein that is found in excitatory synapses opposite the pre… 
Highly Cited
2008
Highly Cited
2008
Pre‐synaptic and post‐synaptic localization of EphA4 and EphB2 in adult mouse forebrain
The ephrin receptors EphA4 and EphB2 have been implicated in synaptogenesis and long‐term potentiation in the cerebral cortex and… 
Review
2006
Review
2006
Molecular organization of the presynaptic active zone
The exocytosis of neurotransmitter-filled synaptic vesicles is under tight temporal and spatial control in presynaptic nerve… 
Highly Cited
2003
Highly Cited
2003
Functional Inactivation of a Fraction of Excitatory Synapses in Mice Deficient for the Active Zone Protein Bassoon
Highly Cited
2001
Highly Cited
2001
Neurobiological effects of a null mutation depend on genetic context: comparison between two hotfoot alleles of the delta-2 ionotropic glutamate receptor
Highly Cited
1999
Highly Cited
1999
Aczonin, a 550-Kd Putative Scaffolding Protein of Presynaptic Active Zones, Shares Homology Regions with Rim and Bassoon and Binds Profilin
Neurotransmitter exocytosis is restricted to the active zone, a specialized area of the presynaptic plasma membrane. We report… 
Highly Cited
1995
Highly Cited
1995
Cellular and subcellular localization of syntaxin-like immunoreactivity in the rat striatum and cortex
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