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presynaptic active zone

Known as: pre-synaptic active zone 
A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Mechanisms regulating the surveillance and clearance of synaptic proteins are not well understood. Intriguingly, the loss of the… Expand
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Review
2009
Review
2009
Rapid neurotransmission depends on the structural and functional integrity of synaptic connections. How synapses assemble is… Expand
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Highly Cited
2009
Highly Cited
2009
The presynaptic proteome controls neurotransmitter release and the short and long term structural and functional dynamics of the… Expand
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Review
2006
Review
2006
The exocytosis of neurotransmitter-filled synaptic vesicles is under tight temporal and spatial control in presynaptic nerve… Expand
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Highly Cited
2004
Highly Cited
2004
The cellular mechanisms involved in the formation of the glutamatergic postsynaptic density (PSD) are mainly unknown. Previous… Expand
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Highly Cited
2003
Highly Cited
2003
Mutant mice lacking the central region of the presynaptic active zone protein Bassoon were generated to establish the role of… Expand
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Highly Cited
2000
Highly Cited
2000
Little is known about presynaptic assembly during central nervous system synaptogenesis. Here we used time-lapse fluorescence… Expand
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Highly Cited
1999
Highly Cited
1999
Neurotransmitter exocytosis is restricted to the active zone, a specialized area of the presynaptic plasma membrane. We report… Expand
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Highly Cited
1992
Highly Cited
1992
Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of… Expand
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Highly Cited
1990
Highly Cited
1990
Calcium ions serve as intracellular messengers in 2 activities of hair cells: in conjunction with Ca2(+)-activated K+ channels… Expand
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