The synaptic proteome

  title={The synaptic proteome},
  author={Melanie La\ssek and Jens Weingarten and Walter Volknandt},
  journal={Cell and Tissue Research},
Synapses are focal hot spots for signal transduction and plasticity in the brain. A synapse comprises an axon terminus, the presynapse, the synaptic cleft containing extracellular matrix proteins as well as adhesion molecules, and the postsynaptic density as target structure for chemical signaling. The proteomes of the presynaptic and postsynaptic active zones control neurotransmitter release and perception. These tasks demand short- and long-term structural and functional dynamics of the… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 134 references

The proteome of the presynaptic active zone from mouse brain

J Weingarten, M Lassek, BF Mueller
Mol Cell Neurosci • 2014
View 20 Excerpts
Highly Influenced

Identification of NEEP21 as a ß-amyloid precursor protein-interacting protein in vivo that modulates amyloidogenic processing in vitro.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2010
View 11 Excerpts
Highly Influenced

Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses

J Boyken, M Gronborg, +3 authors JJ Chua
Neuron • 2013
View 15 Excerpts
Highly Influenced

Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2010
View 4 Excerpts
Highly Influenced

Molecular anatomy of the postsynaptic density.

Molecular and cellular neurosciences • 2007
View 3 Excerpts
Highly Influenced

Molecular Anatomy of a Trafficking Organelle

Cell • 2006
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…