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pranlukast

Known as: 8-(4 (4-phenylbutoxy)benzoyl)amino-2-(tetrazol-5'-yl)-4-oxo-4H-1-benzopyran, N-(4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-p-(4-phenylbutoxy)benzamide 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Anti-Asthmatic AgentsChromonesLeukotriene Antagonists

Narrower (3)

ONO 1078ONO-RS 411SB 205312

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Involvement of cysteinyl leukotriene receptor 1 in Aβ1–42-induced neurotoxicity in vitro and in vivo
Highly Cited
2006
Highly Cited
2006
Increased expression of cysteinyl leukotriene receptor-1 in the brain mediates neuronal damage and astrogliosis after focal cerebral ischemia in rats
Highly Cited
2005
Highly Cited
2005
CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors.
Highly Cited
2004
Highly Cited
2004
Role for cysteinyl leukotrienes in allergen-induced change in circulating dendritic cell number in asthma.
Highly Cited
1999
Highly Cited
1999
Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.
The cysteinyl leukotrienes (CysLTs) have been implicated in the pathophysiology of inflammatory disorders, in particular asthma… 
Highly Cited
1999
Highly Cited
1999
Effects of ONO‐1078 (pranlukast) on cytokine production in peripheral blood mononuclear cells of patients with bronchial asthma
ONO‐1078 (pranlukast) is a leukotriene receptor antagonist developed in Japan. This drug has been shown to be useful in oral… 
Highly Cited
1999
Highly Cited
1999
Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist.
Highly Cited
1998
Highly Cited
1998
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists.
The cysteinyl leukotrienes (CysLTs) mimic many of the features of asthma and are implicated in its pathophysiology. Little… 
Highly Cited
1997
Highly Cited
1997
Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid. The Tokyo Joshi-Idai Asthma Research Group.
To test whether the leukotriene antagonist ONO-1078 (pranlukast) prevents asthma exacerbations during reduction of high-dose… 
Highly Cited
1996
Highly Cited
1996
Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody.
Aerosolized cysteinyl leukotrienes (CysLTs) elicit migration of eosinophils into guinea pig lungs and the airways of patients… 
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