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pranlukast

Known as: 8-(4 (4-phenylbutoxy)benzoyl)amino-2-(tetrazol-5'-yl)-4-oxo-4H-1-benzopyran, N-(4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-p-(4-phenylbutoxy)benzamide 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Anti-Asthmatic AgentsChromonesLeukotriene Antagonists

Narrower (3)

ONO 1078ONO-RS 411SB 205312

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
A double-blind non-inferiority clinical study of montelukast, a cysteinyl leukotriene receptor 1 antagonist, compared with pranlukast in patients with seasonal allergic rhinitis.
BACKGROUND During the course of development of montelukast, a cysteinyl leukotriene receptor 1 antagonist, for treatment of… 
2007
2007
Cysteinyl leukotrienes enhance tumour necrosis factor‐α‐induced matrix metalloproteinase‐9 in human monocytes/macrophages
Background Matrix metalloproteinase‐9 (MMP‐9) is an important enzyme responsible for airway remodelling. Monocytes/macrophages… 
2005
2005
Cysteinyl leukotrienes induce monocyte chemoattractant protein 1 in human monocytes/macrophages
Background Monocytes/macrophages have a cysteinyl leukotriene 1 (CysLT1) receptor, but its function is poorly understood. 
2003
2003
Churg–Strauss syndrome (CSS) in a patient receiving pranlukast
Pranlukast is a cysteinyl leukotriene receptor I antagonist (LTRAs) approved for treatment of asthma in Japan since 1995… 
2003
2003
Inhibition of Human Eosinophil Activation by a Cysteinyl Leukotriene Receptor Antagonist (Pranlukast; ONO-1078)
Eosinophils produce cysteinyl leukotrienes such as leukotriene C4 and D4 upon stimulation by platelet-activating factor or other… 
2001
2001
Effects of Pranlukast, a Leukotriene Receptor Antagonist, on Airway Inflammation in Mild Asthmatics
To determine the anti-inflammatory actions of pranlukast, a cysteinyl leuklotriene receptor antagonist, we measured exhaled… 
Highly Cited
1999
Highly Cited
1999
Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist.
1998
1998
Effects of the cysteinyl leukotriene receptor antagonists pranlukast and zafirlukast on tracheal mucus secretion in ovalbumin‐sensitized guinea‐pigs in vitro
We investigated the inhibitory effects of the cysteinyl leukotriene (CysLT1) receptor antagonists, pranlukast and zafirlukast, on… 
1997
1997
Effect of pranlukast, an oral leukotriene receptor antagonist, on leukotriene D4 (LTD4) challenge in normal volunteers.
BACKGROUND: There is increasing evidence to show that leukotrienes are important mediators in asthma. Leukotriene receptor… 
1996
1996
The pharmacokinetics of pranlukast in healthy young and elderly subjects.
Pranlukast is a novel LTD4 antagonist under development for the treatment of asthma. To assess the effect of age, the… 
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