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ONO 1078

Known as: ONO-1078 
 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
AIM To determine whether ONO-1078 [pranlukast, 4-oxo-8-[p-(4-phenylbutyloxy)benzoyl-amono]-2-(tetrazol-5-yl)-4H-1-benzopyran… Expand
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Highly Cited
1999
Highly Cited
1999
ONO‐1078 (pranlukast) is a leukotriene receptor antagonist developed in Japan. This drug has been shown to be useful in oral… Expand
Highly Cited
1997
Highly Cited
1997
To test whether the leukotriene antagonist ONO-1078 (pranlukast) prevents asthma exacerbations during reduction of high-dose… Expand
Highly Cited
1996
Highly Cited
1996
Aerosolized cysteinyl leukotrienes (CysLTs) elicit migration of eosinophils into guinea pig lungs and the airways of patients… Expand
Highly Cited
1994
Highly Cited
1994
We evaluated the effect of ONO-1078, a selective leukotriene-C4, -D4, and -E4-receptor antagonist, on bronchoconstriction… Expand
Highly Cited
1993
Highly Cited
1993
To evaluate the involvement of sulphidopeptide leukotrienes on bronchial hyperresponsiveness in asthma, we examined the effects… Expand
Highly Cited
1993
Highly Cited
1993
Peptide leukotrienes have been suggested to play an important role in bronchial asthma. As antigen-induced bronchoconstrictions… Expand
Highly Cited
1993
Highly Cited
1993
BACKGROUND Cysteinyl leukotrienes are potent contractile agonists for airway smooth muscle. To examine the relative role of… Expand
Highly Cited
1992
Highly Cited
1992
We evaluated the antagonist activity of ONO-1078 against peptide leukotrienes (LTs) by a radioligand binding assay and functional… Expand
Highly Cited
1992
Highly Cited
1992
We investigated the in vivo antagonistic activity of ONO-1078 against peptide leukotrienes (LTs) in guinea pigs. ONO-1078, when… Expand