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ONO 1078
Known as:
ONO-1078
National Institutes of Health
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1 relation
Broader (1)
pranlukast
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice
Guo-liang Yu
,
E. Wei
,
+9 authors
Li-hui Zhang
Brain Research
2005
Corpus ID: 28339317
Highly Cited
2003
Highly Cited
2003
Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on transient global cerebral ischemia in rats.
Li-hui Zhang
,
E. Wei
Acta Pharmacologica Sinica
2003
Corpus ID: 10875826
AIM To determine whether ONO-1078 [pranlukast, 4-oxo-8-[p-(4-phenylbutyloxy)benzoyl-amono]-2-(tetrazol-5-yl)-4H-1-benzopyran…
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2002
2002
Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on focal cerebral ischemia in rats.
Wei-Ping Zhang
,
E. Wei
,
Ru-huan Mei
,
Chao-yang Zhu
,
Meng-hui Zhao
Acta Pharmacologica Sinica
2002
Corpus ID: 32079064
AIM To determine whether ONO-1078 (pranlukast), a potent leukotriene receptor antagonist, has neuroprotective effect on focal…
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Highly Cited
1999
Highly Cited
1999
Effects of ONO‐1078 (pranlukast) on cytokine production in peripheral blood mononuclear cells of patients with bronchial asthma
Tohda
,
Nakahara
,
Kubo
,
Haraguchi
,
Fukuoka
,
Nakajima
Clinical and Experimental Allergy
1999
Corpus ID: 21163922
ONO‐1078 (pranlukast) is a leukotriene receptor antagonist developed in Japan. This drug has been shown to be useful in oral…
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Highly Cited
1997
Highly Cited
1997
Leukotriene antagonist prevents exacerbation of asthma during reduction of high-dose inhaled corticosteroid. The Tokyo Joshi-Idai Asthma Research Group.
J. Tamaoki
,
M. Kondo
,
+5 authors
K. Konno
American Journal of Respiratory and Critical Care…
1997
Corpus ID: 42660427
To test whether the leukotriene antagonist ONO-1078 (pranlukast) prevents asthma exacerbations during reduction of high-dose…
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Highly Cited
1996
Highly Cited
1996
Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody.
D. Underwood
,
R. Osborn
,
S. J. Newsholme
,
T. Torphy
,
D. Hay
American Journal of Respiratory and Critical Care…
1996
Corpus ID: 25417912
Aerosolized cysteinyl leukotrienes (CysLTs) elicit migration of eosinophils into guinea pig lungs and the airways of patients…
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Highly Cited
1994
Highly Cited
1994
Inhibition of analgesic-induced asthma by leukotriene receptor antagonist ONO-1078.
H. Yamamoto
,
M. Nagata
,
+5 authors
Y. Dohi
American Journal of Respiratory and Critical Care…
1994
Corpus ID: 5805558
We evaluated the effect of ONO-1078, a selective leukotriene-C4, -D4, and -E4-receptor antagonist, on bronchoconstriction…
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Highly Cited
1992
Highly Cited
1992
In vivo pharmacologic profile of ONO-1078: a potent, selective and orally active peptide leukotriene (LT) antagonist.
N. Nakagawa
,
T. Obata
,
+4 authors
H. Aishita
Japanese Journal of Pharmacology
1992
Corpus ID: 25678190
We investigated the in vivo antagonistic activity of ONO-1078 against peptide leukotrienes (LTs) in guinea pigs. ONO-1078, when…
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Highly Cited
1992
Highly Cited
1992
In vitro antagonism of ONO-1078, a newly developed anti-asthma agent, against peptide leukotrienes in isolated guinea pig tissues.
T. Obata
,
Y. Okada
,
M. Motoishi
,
N. Nakagawa
,
T. Terawaki
,
H. Aishita
Japanese Journal of Pharmacology
1992
Corpus ID: 2671549
We evaluated the antagonist activity of ONO-1078 against peptide leukotrienes (LTs) by a radioligand binding assay and functional…
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1988
1988
The effects of lipoxygenase inhibitor and peptidoleukotriene antagonist on myocardial injury in a canine coronary occlusion-reperfusion model.
Y. Toki
,
N. Hieda
,
+4 authors
T. Satake
Prostaglandins
1988
Corpus ID: 23620136
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