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posaconazole

Known as: posaconazole [Chemical/Ingredient] 
A broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome… 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2014
Highly Cited
2014
BACKGROUND Current therapeutic options for Chagas' disease are limited to benznidazole and nifurtimox, which have been associated… 
Review
2010
Review
2010
Posaconazole is a recently approved lipophilic triazole antifungal agent that exhibits potent and broad-spectrum antifungal… 
Highly Cited
2007
Highly Cited
2007
BACKGROUND Patients with neutropenia resulting from chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome… 
Highly Cited
2007
Highly Cited
2007
BACKGROUND Invasive fungal infections are an important cause of morbidity and mortality after allogeneic hematopoietic stem-cell… 
Review
2007
Review
2007
BACKGROUND Invasive aspergillosis is an important cause of morbidity and mortality in immunocompromised patients. Current… 
Highly Cited
2006
Highly Cited
2006
To evaluate the activity of posaconazole for treatment of zygomycosis, a disease for which therapeutic options are limited, we… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT Zygomycosis, an infection that is associated with significant morbidity and mortality, is becoming common in… 
Highly Cited
2006
Highly Cited
2006
BACKGROUND Conventional amphotericin B-based antifungal therapy for invasive fusariosis in patients with a hematologic malignancy… 
Highly Cited
2004
Highly Cited
2004
AIMS This randomized, crossover, single-dose study evaluated the relative oral bioavailability of posaconazole suspension and…