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posaconazole

Known as: posaconazole [Chemical/Ingredient] 
A broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Current therapeutic options for Chagas' disease are limited to benznidazole and nifurtimox, which have been associated… Expand
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Highly Cited
2009
Highly Cited
2009
An increase in the frequency of azole-resistant Aspergillus fumigatus has emerged. 
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Patients with neutropenia resulting from chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Invasive fungal infections are an important cause of morbidity and mortality after allogeneic hematopoietic stem-cell… Expand
Review
2007
Review
2007
BACKGROUND Invasive aspergillosis is an important cause of morbidity and mortality in immunocompromised patients. Current… Expand
Highly Cited
2006
Highly Cited
2006
To evaluate the activity of posaconazole for treatment of zygomycosis, a disease for which therapeutic options are limited, we… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Zygomycosis, an infection that is associated with significant morbidity and mortality, is becoming common in… Expand
Highly Cited
2006
Highly Cited
2006
BACKGROUND Conventional amphotericin B-based antifungal therapy for invasive fusariosis in patients with a hematologic malignancy… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT The in vitro activity of the novel triazole antifungal agent posaconazole (Noxafil; SCH 56592) was assessed in 45… Expand
Highly Cited
2004
Highly Cited
2004
AIMS This randomized, crossover, single-dose study evaluated the relative oral bioavailability of posaconazole suspension and… Expand
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