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posaconazole

Known as: posaconazole [Chemical/Ingredient] 
A broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome… 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (4)

14-alpha Demethylase InhibitorsAntifungal AgentsTriazolesTrypanocidal Agents
16.7 ML posaconazole 18 MG/ML Injection [Noxafil]AzolesMycosesPosaconazole:MCnc:Pt:Ser/Plas:Qn

Narrower (2)

NoxafilSCH-56592

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Phase 3 pharmacokinetics and safety study of a posaconazole tablet formulation in patients at risk for invasive fungal disease.
BACKGROUND Antifungal prophylaxis with a new oral tablet formulation of posaconazole may be beneficial to patients at high risk… 
Highly Cited
2014
Highly Cited
2014
Azole-resistant Aspergillus fumigatus with the environmental TR46/Y121F/T289A mutation in India.
resistant A. fumigatus strains originated from Varanasi, five from a potato (Solanum tuberosum) field and one from a fenugreek… 
Review
2012
Review
2012
Posaconazole Exposure-Response Relationship: Evaluating the Utility of Therapeutic Drug Monitoring
ABSTRACT Posaconazole has become an important part of the antifungal armamentarium in the prophylaxis and salvage treatment of… 
Highly Cited
2012
Highly Cited
2012
Guideline vulvovaginal candidosis (2010) of the german society for gynecology and obstetrics, the working group for infections and infectimmunology in gynecology and obstetrics, the german society of…
Candida (C.) species colonize the estrogenized vagina in at least 20% of all women. This statistic rises to 30% in late pregnancy… 
Highly Cited
2012
Highly Cited
2012
Recent Developments in Sterol 14-demethylase Inhibitors for Chagas Disease.
  • F. BucknerJ. Urbina
  • International Journal for Parasitology: Drugs and…
  • 2012
  • Corpus ID: 27336471
Highly Cited
2010
Highly Cited
2010
Method for therapeutic drug monitoring of azole antifungal drugs in human serum using LC/MS/MS.
Highly Cited
2008
Highly Cited
2008
Posaconazole vs. Fluconazole or Itraconazole Prophylaxis in Patients with Neutropenia
Review
2007
Review
2007
Recent advances in antifungal chemotherapy.
Highly Cited
2004
Highly Cited
2004
Aspergillus terreus
Invasive aspergillosis (IA) has emerged as a common cause of morbidity and mortality among immunocompromised patients. At The… 
Review
2001
Review
2001
Lipid-based amphotericin B: a review of the last 10 years of use.
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