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ponatinib hydrochloride

Known as: Benzamide, 3-(2-Imidazo(1,2-B)Pyridazin-3-Ylethynyl)-4-Methyl-N-(4-((4-Methyl-1- Piperazinyl)Methyl)-3-(Trifluoromethyl)Phenyl)-, Hydrochloride (1:1) 
The hydrochloride salt form of an orally bioavailable multitargeted receptor tyrosine kinase (RTK) inhibitor with potential antiangiogenic and… 
National Institutes of Health

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Iclusig
Receptor Tyrosine Kinase Inhibitionponatinibponatinib 45 MG Oral Tablet [Iclusig]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Loss of SYK and LYN Tyrosine Kinase Expression Impair Ponatinib-Induced Apoptosis in K 562 Cells
Targeting the tyrosine kinase activity of BCR-ABL is the gold standard strategy in Chronic Myeloid Leukemia (CML) for the last… 
2016
2016
Evaluation of Efficacy and Safety of Ponatinib as Third-line Treatment in Patients with the Diagnosis of Chronic Phase Chronic Myeloid Leukemia
Philadelphia (Ph) is a fusion protein product of BCRABL and is a structurally active tyrosine kinase that causes chronic myeloid… 
2014
2014
Ponatinib nel trattamento della leucemia
2013
2013
Cancer Therapy : Preclinical See related commentary by Dao and Tyner , p . 1309 Combination of Ponatinib with Hedgehog Antagonist Vismodegib for Therapy-Resistant BCR-ABL 1 – Positive Leukemia
Purpose: The Hedgehog signaling pathway is a key regulator of cell growth and differentiation during development. Whereas the… 
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