polytheonamide B
National Institutes of Health
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The β6.3-helical channel of the marine cytotoxic peptide, polytheonamide B (pTB), is examined in water, the POPC bilayer, and a 1…
Polytheonamide B (1) is a natural peptide that displays potent cytotoxicity against P388 mouse leukemia cells (IC50 =0.098 nm…
The cytotoxic 48-mer peptide, polytheonamide B (pTB), from a marine sponge forms a β6.3-helix with an inner diameter of 4 Å and a…
Polytheonamide B (1), isolated from the marine sponge Theonella swinhoei, is a posttranslationally modified ribosomal peptide (MW…
Polytheonamide B (1) is an ion-channel forming natural peptide with a d,l-alternating 48 amino acid sequence, which is an…
Chemical point mutation: Polytheonamide B is a naturally occurring polypeptide containing 48 amino acids. It both displays potent…
1 couldserve as a minimum-structure platform for investigatingrequirements for ion-channel functions and designing…
A highly cytotoxic extract from marine sponge, polytheonamide B, is a linear 48-residue peptide. Alternative D- and L-forms of…