Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,299 papers from all fields of science
Search
Sign In
Create Free Account
polyketide biosynthetic process
Known as:
polyketide anabolism
, polyketide synthesis
, polyketide formation
Expand
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
negative regulation of polyketide biosynthetic process
positive regulation of polyketide biosynthetic process
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
The biochemical basis for stereochemical control in polyketide biosynthesis.
C. Valenzano
,
R. Lawson
,
A. Chen
,
C. Khosla
,
D. Cane
Journal of the American Chemical Society
2009
Corpus ID: 207149371
One of the most striking features of complex polyketides is the presence of numerous methyl- and hydroxyl-bearing stereogenic…
Expand
Highly Cited
2006
Highly Cited
2006
Roles of the Active Site Water, Histidine 303, and Phenylalanine 396 in the Catalytic Mechanism of the Elongation Condensing Enzyme of Streptococcus pneumoniae*
Yong-mei Zhang
,
J. Hurlbert
,
S. White
,
C. Rock
Journal of Biological Chemistry
2006
Corpus ID: 44613772
β-Ketoacyl-ACP synthases catalyze the condensation steps in fatty acid and polyketide synthesis and are targets for the…
Expand
2005
2005
The Lego-ization of polyketide biosynthesis
D. Sherman
Nature Biotechnology
2005
Corpus ID: 28113664
A modular method for assembling polyketide synthases accelerates the generation of new polyketides.
Highly Cited
2004
Highly Cited
2004
Development of a high cell-density fed-batch bioprocess for the heterologous production of 6-deoxyerythronolide B in Escherichia coli.
J. Lau
,
C. Tran
,
P. Licari
,
J. Galazzo
Journal of Biotechnology
2004
Corpus ID: 367521
2004
2004
Stereochemically rich pentaketides from bis(isoxazolines): a general strategy for efficient polyketide synthesis.
L. Fader
,
E. Carreira
Organic Letters
2004
Corpus ID: 34973989
[reaction: see text] A strategy based on diastereoselective dipolar cycloaddition reaction of nitrile oxides and allylic…
Expand
Highly Cited
2002
Highly Cited
2002
A Novel Biosynthetic Pathway Providing Precursors for Fatty Acid Biosynthesis and Secondary Metabolite Formation in Myxobacteria*
T. Mahmud
,
H. Bode
,
+5 authors
R. Müller
Journal of Biological Chemistry
2002
Corpus ID: 3261051
Short chain carboxylic acids are well known as the precursors of fatty acid and polyketide biosynthesis. Iso-fatty acids, which…
Expand
Review
2001
Review
2001
Type I polyketide biosynthesis in bacteria (part B).
B. Rawlings
Natural product reports (Print)
2001
Corpus ID: 20404515
Review
2001
Review
2001
Engineering of complex polyketide biosynthesis — insights from sequencing of the monensin biosynthetic gene cluster
P. Leadlay
,
J. Staunton
,
+13 authors
C. Wilkinson
Journal of Industrial Microbiology…
2001
Corpus ID: 12322655
The biosynthesis of complex reduced polyketides is catalysed in actinomycetes by large multifunctional enzymes, the modular Type…
Expand
1996
1996
Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates.
R. Pieper
,
S. Ebert-Khosla
,
D. Cane
,
C. Khosla
Biochemistry
1996
Corpus ID: 12469737
6-Deoxyerythronolide B synthase (DEBS) is a modular polyketide synthase (PKS) that catalyzes the biosynthesis of the parent…
Expand
Highly Cited
1992
Highly Cited
1992
6-Deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme.
D. Bevitt
,
J. Cortés
,
S. Haydock
,
P. Leadlay
European Journal of Biochemistry
1992
Corpus ID: 35042441
Sequencing of the eryA region of the erythromycin biosynthetic gene cluster from Saccharopolyspora erythraea has revealed another…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE