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polygalasaponin F

National Institutes of Health

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SaponinsTriterpenes

Papers overview

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2020
2020
Polygalasaponin F (PGSF) Inhibits Neuronal Apoptosis Induced by Oxygen-Glucose Deprivation and Reoxygenation through the PI3K/Akt Pathway.
Cerebral ischaemia is a common cerebrovascular disease and often induces neuronal apoptosis, leading to brain damage… 
2019
2019
Protective effects of polygalasaponin F on oxidative stress and apoptosis-induced ischemic myocardial injury in neonatal rats with hypoxic-ischemic brain damage.
The aim of the present study was to evaluate the role of polygalasaponin F on ischemic myocardial injury in neonatal rats with… 
2015
2015
The molecular mechanism of polygalasaponin F-mediated decreases in TNFα: emphasizing the role of the TLR4-PI3K/AKT-NF-κB pathway
Polygalasaponin F (PS-F), an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the… 
2014
2014
Polygalasaponin F against rotenone-induced apoptosis in PC12 cells via mitochondria protection pathway
To investigate the protective effect and the underlying mechanism of polygalasaponin F (PS-F) against rotenone-induced PC12 cells… 
2012
2012
Polygalasaponin F induces long-term potentiation in adult rat hippocampus via NMDA receptor activation
Aim:To investigate the effect and underlying mechanisms of polygalasaponin F (PGSF), a triterpenoid saponin isolated from… 
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