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polyamine biosynthetic process

Known as: polyamine synthesis, polyamine anabolism, polyamine formation 
The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. [ISBN… (More)

Topic mentions per year

Topic mentions per year

1970-2018
0204019702018

Papers overview

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Review
2015
Review
2015
Polyamines function in stress tolerance: from synthesis to regulation
Plants are challenged by a variety of biotic or abiotic stresses, which can affect their growth and development, productivity… (More)
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2005
2005
Polyamine synthesis from proline in the developing porcine placenta.
Polyamines (putrescine, spermidine, and spermine) are essential for placental growth and angiogenesis. However, little is known… (More)
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2004
2004
Effect of reduced arginine decarboxylase activity on salt tolerance and on polyamine formation during salt stress in Arabidopsis thaliana.
Polyamines have been suggested to play an important role in stress protection. However, attempts to determine the function of… (More)
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2000
2000
Arginase I: a limiting factor for nitric oxide and polyamine synthesis by activated macrophages?
Because arginase hydrolyzes arginine to produce ornithine and urea, it has the potential to regulate nitric oxide (NO) and… (More)
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1999
1999
Inhibition of polyamine synthesis induces p53 gene expression but not apoptosis.
The nuclear phosphoprotein p53 acts as a transcription factor and is involved in growth inhibition and apoptosis. The present… (More)
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1998
1998
Expression of the transforming growth factor-beta gene during growth inhibition following polyamine depletion.
Polyamine depletion and cytokine transforming growth factor-beta (TGF-beta) inhibit cell proliferation. The current study tests… (More)
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1987
1987
Relative abilities of bis(ethyl) derivatives of putrescine, spermidine, and spermine to regulate polyamine biosynthesis and inhibit L1210 leukemia cell growth.
It has been shown previously (Porter et al., Cancer Res., 45: 2050-2057, 1985) that the N1,N8-bis(ethyl) derivative of spermidine… (More)
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1986
1986
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
alpha-Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, blocks polyamine synthesis and has… (More)
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1985
1985
Treatment of gambiense sleeping sickness in the Sudan with oral DFMO (DL-alpha-difluoromethylornithine), an inhibitor of ornithine decarboxylase; first field trial.
Difluoromethylornithine (DFMO), a specific, irreversible inhibitor of polyamine biosynthesis shown to be curative in animal… (More)
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1983
1983
Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by alpha-difluoromethylornithine.
Application of the tumor-promoting agent 12-O-tetradecanoylphorbol-13-acetate (TPA) to mouse skin leads to a manifold induction… (More)
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