poly A specific exoribonuclease

Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease that efficiently degrades poly(A) tails and regulates, in part, mRNA… Expand

In the Archaea only a handful of ribonucleases involved in RNA processing and degradation have been characterized. One potential… Expand

The major cytoplasmic 5' to 3'-exoribonuclease activity is carried out by the Xrn1 protein in eukaryotic cells. A number of… Expand

A 3'-exoribonuclease complex, termed the exosome, has important functions in the cytoplasm, as well as in the nucleus, and is… Expand

Poly(A)-specific ribonuclease (PARN) is a cap-interacting and poly(A)-specific 3′-exoribonuclease. Here we have investigated how… Expand

The Saccharomyces cerevisiae OLE1 gene encodes the Δ-9 fatty acid desaturase, a highly regulated integral membrane enzyme… Expand

RNA turnover in eukaryotes is thought to require 3'-exonuclease activity but so far no RNase with that specificity has been… Expand

The 2',5'-oligoadenylate system (2-5A system) has an essential role in the establishment of the antiviral state of cells exposed… Expand

After infection of the respective target cells with the human immunodeficiency virus (HIV-1) viral progeny is produced only after… Expand