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pneumococcal surface protein A

Known as: PspA protein, Streptococcus pneumoniae 
National Institutes of Health

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Broader (1)

Bacterial Proteins

Papers overview

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2015
2015
A bivalent conjugate vaccine containing PspA families 1 and 2 has the potential to protect against a wide range of Streptococcus pneumoniae strains and Salmonella Typhi.
2010
2010
Helper T Cell Epitope-Mapping Reveals MHC-Peptide Binding Affinities That Correlate with T Helper Cell Responses to Pneumococcal Surface Protein A
Understanding the requirements for protection against pneumococcal carriage and pneumonia will greatly benefit efforts in… 
2008
2008
The round window membrane in otitis media: effect of pneumococcal proteins.
OBJECTIVE To determine whether mutants of Streptococcus pneumoniae that are deficient in pneumococcal surface protein A (PspA… 
2008
2008
Role of Pneumococcal Proteins in Sensorineural Hearing Loss Due to Otitis Media
Hypothesis: Two Streptococcus pneumoniae proteins, pneumococcal surface protein A (PspA) and pneumolysin (Ply), have functional… 
2007
2007
Pneumococcal surface protein A family types of Streptococcus pneumoniae from community-acquired pneumonia patients in Japan
We assessed pneumococcal surface protein A (PspA) family types of 141 isolates of Streptococcus pneumoniae from community… 
2006
2006
DNA vaccines expressing pneumococcal surface protein A (PspA) elicit protection levels comparable to recombinant protein.
Pneumococcal surface protein A (PspA) is a promising candidate for the development of cost-effective vaccines against… 
2004
2004
Invasive Streptococcus pneumoniae isolates from Argentinian children: serotypes, families of pneumococcal surface protein A (PspA) and genetic diversity
PspA is an antigenically variable virulence factor of Streptococcus pneumoniae that inhibits complement deposition and is a… 
Review
2004
Review
2004
Protection of the elderly from pneumococcal pneumonia with a protein-based vaccine?
2002
2002
The Mechanism Underlying T Cell Help for Induction of an Antigen-Specific In Vivo Humoral Immune Response to Intact Streptococcus pneumoniae Is Dependent on the Type of Antigen1
Little is known concerning the role of T cells in regulating an anti-polysaccharide Ig response to an intact pathogen. We… 
1997
1997
Immunization with a plasmid expressing pneumococcal surface protein A (PspA) can elicit protection against fatal infection with Streptococcus pneumoniae
Pneumococcal surface protein A (PspA) is a protection-eliciting protein of Streptococcus pneumoniae. We observed that… 
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