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pleconaril

Known as: 3-(3,5-dimethyl-4((3-(3-methyl-5-isoxazolyl)propyl)phenyl)-5-trifluoromethyl)-1,2,4-oxadiazole, 3-[3,5-Dimethyl-4-[3-(3-Methyl-5-Isoxazolyl)Propoxy]Phenyl]-5-(Trifluoromethyl)-1,2,4-Oxadiazole 
A small-molecule inhibitor with activity against viruses in the picornaviridae family, including enterovirus and rhinovirus. Pleconaril binds to a… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antiviral AgentsOxadiazoles

Narrower (1)

Picovir

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Soluble coxsackie- and adenovirus receptor (sCAR-Fc); a highly efficient compound against laboratory and clinical strains of coxsackie-B-virus.
2013
2013
Rapid and convenient assays to assess potential inhibitory activity on in vitro hepatitis A replication.
2004
2004
Double-blind Placebo-controlled Trial of Pleconaril in Infants
2003
2003
SPECT scans for monitoring response to pleconaril therapy in chronic enteroviral meningoencephalitis.
Chronic enteroviral meningoencephalitis (CEMA) is a rare complication of immunodeficient individuals and may present as insidious… 
2001
2001
Treatment of ALS with pleconaril
Enteroviral RNA sequences were identified in spinal cords from 15 of 17 patients with ALS using reverse transcriptase PCR (RT-PCR… 
Review
2001
Review
2001
WITHDRAWN: Antivirals for the common cold.
BACKGROUND The common cold is a ubiquitous short and usually mild illness for which preventive and treatment interventions have… 
Review
2000
Review
2000
Influenza virus and rhinovirus-related otitis media: potential for antiviral intervention
Review
2000
Review
2000
Pleconaril Sanofi Synthélabo/ViroPharma.
Pleconaril is an oral antiviral agent being developed by ViroPharma and Sanofi-Synthélabo (formerly Sterling Winthrop) for the… 
1999
1999
Pleconaril. A broad spectrum antipicornaviral agent.
1999
1999
Oral Pleconaril Reduces the Duration and Severity of Enteroviral Meningitis in Children
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