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Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats.
  • S. Lau, P. Woo, K. Yuen
  • Biology
    Proceedings of the National Academy of Sciences…
  • 27 September 2005
In a surveillance study for CoV in noncaged animals from the wild areas of the Hong Kong Special Administration Region, a CoV closely related to SARS-CoV is identified from 23 (39%) of 59 anal swabs of wild Chinese horseshoe bats by using RT-PCR and the presence of a 29-bp insertion in ORF 8 of bat-SARS- coV genome suggests that it has a common ancestor with civet SARS -CoV.
Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses
It appears that bats and birds, the warm blooded flying vertebrates, are ideal hosts for the coronavirus gene source and birds for Gammacoronavirus and Deltacor onavirus, to fuel coronav virus evolution and dissemination.
Characterization and Complete Genome Sequence of a Novel Coronavirus, Coronavirus HKU1, from Patients with Pneumonia
The data support the existence of a novel group 2 coronavirus associated with pneumonia in humans, CoV-HKU1, from a 71-year-old man with pneumonia who had just returned from Shenzhen, China.
Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia
Summary.Phylogenetic trees constructed using predicted amino acid sequences of putative proteins of coronavirus HKU1 (CoV-HKU1) revealed that CoV-HKU1 formed a distinct branch among group 2
Coronavirus Genomics and Bioinformatics Analysis
Coronaviruses possess the largest genomes among all known RNA viruses, with G + C contents varying from 32% to 43%.
Coronavirus Diversity, Phylogeny and Interspecies Jumping
The present evidence supports that bat coronaviruses are the gene pools of group 1 and 2 coronaviraluses, whereas bird coronavirus are the genes of group 3 coronavIRuses.
Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease
Developing an effective camel MERS-CoV vaccine and implementing appropriate infection control measures may control the continuing epidemic.
Severe Acute Respiratory Syndrome Coronavirus as an Agent of Emerging and Reemerging Infection
The findings that horseshoe bats are the natural reservoir for SARS-CoV-like virus and that civets are the amplification host highlight the importance of wildlife and biosecurity in farms and wet markets, which can serve as the source and amplification centers for emerging infections.
Clinical Features and Complete Genome Characterization of a Distinct Human Rhinovirus (HRV) Genetic Cluster, Probably Representing a Previously Undetected HRV Species, HRV-C, Associated with Acute
It is revealed that a newly identified HRV species, HRV-C, is circulating worldwide and is an important cause of febrile wheeze and asthmatic exacerbations in children requiring hospitalization.
Coronavirus HKU1 and Other Coronavirus Infections in Hong Kong
In this 12-month prospective study, nasopharyngeal aspirates from patients with acute respiratory tract infections were subjected to reverse transcription-PCRs specific for CoV-HKU1 and human coronaviruses NL63, OC43, and 229E, and upper respiratory infection was the most common presentation.