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platelet protein P47

Known as: 47KDa platelet protein, platelet 47k protein, pleckstrin 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Blood ProteinsPhosphoproteins
PLEK gene

Narrower (2)

PLEK protein, humanPlek protein, mouse

Papers overview

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Highly Cited
2008
Highly Cited
2008
Proteasome subunit Rpn13 is a novel ubiquitin receptor
Proteasomal receptors that recognize ubiquitin chains attached to substrates are key mediators of selective protein degradation… Expand
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Highly Cited
2008
Highly Cited
2008
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction
Targeted protein degradation is largely performed by the ubiquitin–proteasome pathway, in which substrate proteins are marked by… Expand
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Highly Cited
2004
Highly Cited
2004
Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in…
The mechanisms by which agonists activate glycoprotein (GP) IIb-IIIa function remain unclear. We have reported data on a patient… Expand
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Highly Cited
2004
Highly Cited
2004
Genetically encoded FRET probe for PKC activity based on pleckstrin.
We developed a probe for investigating protein kinase C (PKC) activity in living cells. The probe is based on a fragment of… Expand
Highly Cited
1997
Highly Cited
1997
Pleckstrin Associates with Plasma Membranes and Induces the Formation of Membrane Projections: Requirements for Phosphorylation and the NH2-terminal PH Domain
Pleckstrin homology (PH) domains are sequences of ∼100 amino acids that form “modules” that have been proposed to facilitate… Expand
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Highly Cited
1995
Highly Cited
1995
Protein Kinase C Regulates Pleckstrin by Phosphorylation of Sites Adjacent to the N-terminal Pleckstrin Homology Domain (*)
Pleckstrin is a substrate for protein kinase C in activated platelets that contains at its N and C termini two of the pleckstrin… Expand
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Highly Cited
1995
Highly Cited
1995
Phosphatidylinositol(3, 4, 5) -Trisphosphate Stimulates Phosphorylation of Pleckstrin in Human Platelets (*)
We have reported that platelets exposed to thrombin or thrombin receptor-directed ligand activate phospholipase C and rapidly… Expand
Review
1994
Review
1994
Pleckstrin homology (PH) domains in signal transducton
A diverse array of molecules involved in signal transduction have recently been recognised as containing a new homology domain… Expand
1992
1992
Suppression by wortmannin of platelet responses to stimuli due to inhibition of pleckstrin phosphorylation.
Studies were made of inhibition by wortmannin, a fungal metabolite, of human platelet responses to various stimuli. Wortmannin at… Expand
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Highly Cited
1989
Highly Cited
1989
Molecular analysis of pleckstrin: The major protein kinase c substrate of platelets
Activation of protein kinase C (PKC) in platelets causes the immediate phosphorylation of pleckstrin, an apparent Mr 40–47,000… Expand
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