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platelet protein P47

Known as: 47KDa platelet protein, platelet 47k protein, pleckstrin 
 
National Institutes of Health

Papers overview

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2009
2009
Pleckstrin, the platelet and leukocyte C kinase substrate, is a prominent substrate of PKC in platelets, monocytes, macrophages… Expand
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Highly Cited
2008
Highly Cited
2008
Proteasomal receptors that recognize ubiquitin chains attached to substrates are key mediators of selective protein degradation… Expand
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Highly Cited
2008
Highly Cited
2008
Targeted protein degradation is largely performed by the ubiquitin–proteasome pathway, in which substrate proteins are marked by… Expand
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2007
2007
The protein kinase C (PKC) family of intracellular enzymes plays a crucial role in signal transduction for a variety of cellular… Expand
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Highly Cited
2004
Highly Cited
2004
We developed a probe for investigating protein kinase C (PKC) activity in living cells. The probe is based on a fragment of… Expand
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Highly Cited
2004
Highly Cited
2004
The mechanisms by which agonists activate glycoprotein (GP) IIb-IIIa function remain unclear. We have reported data on a patient… Expand
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2000
2000
Previous experiments suggest that actin disassembly, perhaps at a specific site, is required for platelet secretion. Platelet… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT In the present study, we have addressed the role of the linker for activation of T cells (LAT) in the regulation of… Expand
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1997
1997
Pleckstrin homology (PH) domains are sequences of ∼100 amino acids that form “modules” that have been proposed to facilitate… Expand
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1995
1995
Pleckstrin is a substrate for protein kinase C in activated platelets that contains at its N and C termini two of the pleckstrin… Expand
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