pirprofen

Although many steatogenic drugs inhibit mitochondrial fatty acid beta-oxidation, limited information is available on possible… (More)

BACKGROUND/AIMS Several liver diseases that are characterized by chronic steatosis lead to steatohepatitis lesions in some… (More)

Acylglucuronide formation from the 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen, three nonsteroidal anti… (More)

The interaction of pirprofen with human serum albumin (HSA) was investigated by equilibrium dialysis and spectroscopic (UV… (More)

Administration of pirprofen may produce microvesicular steatosis of the liver in humans. The effects of pirprofen on the… (More)

We provide evidence that both Diclofenac and Pirprofen, two cyclooxygenase inhibitors with a potent analgesic effect both in the… (More)

We report the cases of 2 female patients aged 69 and 61 yr, suffering from fulminant hepatitis induced by pirprofen, a new… (More)

Plasma concentrations of pirprofen were measured in 11 elderly arthritic patients and 6 healthy young volunteers at the beginning… (More)

Pirprofen was well absorbed by man, rhesus monkey, rat, and mouse after oral administration of a solution of 14C-labeled compound… (More)

Pirprofen (800 mg/day) or aspirin (3,600 mg/day) was administered in double-blind fashion for up to one year to 40 adult… (More)