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Compounds were evaluated for antiviral activity in rhabdomyosarcoma (RD) cells against a recent 2014 clinical isolate of… Expand BackgroundRhinovirus infections do not only cause common colds, but may also trigger severe exacerbations of asthma and chronic… Expand ABSTRACT We investigated the susceptibility of 10 enterovirus D68 (EV-D68) isolates (belonging to clusters A, B, and C) to… Expand ABSTRACT Human rhinovirus type C (HRV-C) is a newly discovered enterovirus species frequently associated with exacerbation of… Expand ABSTRACT Picornaviruses (PV) include human rhinovirus (HRV), the primary cause of the common cold, and the enteroviruses (EV… Expand Two hundred and forty pyridazinamine derivates were assayed for their ability to stabilize the Oral Polio Vaccine (OPV). Of these… Expand A randomized, double-blind, placebo-controlled trial assessed the therapeutic efficacy of intranasal pirodavir in naturally… Expand For many years there has been an intensive search for antivirals that are active against rhinoviruses. The reason is very simple… Expand Pirodavir (R77975) is a capsid-binding, antipicornaviral agent with in vitro activity against most rhinovirus (RV) serotypes. We… Expand Pirodavir (R 77975) is the prototype of a novel class of broad-spectrum antipicornavirus compounds. Although its predecessor, R… Expand