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pirlindole

Known as: pyrlindole, pirlindol, 1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-, monohydrochloride 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antidepressive AgentsAntineoplastic AgentsCarbazolesMonoamine Oxidase Inhibitors

Narrower (1)

pirlindole hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Pirlindole in the Treatment of Depression
AbstractBackground: Depressive disorders are common health problems. Both preclinical and clinical studies have shown that… 
1998
1998
Comparative study of pirlindole, a selective RIMA, and its two enantiomers using biochemical and behavioural techniques
The interaction with monoamine oxidase A (MAO-A) and B has been shown to be sensitive to the absolute configuration of molecules… 
1997
1997
Double‐blind randomized controlled study of the efficacy and tolerability of two reversible monoamine oxidase A inhibitors, pirlindole and moclobemide, in the treatment of depression
The aim of this double‐blind randomized study was to compare the efficacy and the tolerability of moclobemide (300‐600 mg daily… 
1996
1996
A double‐blind randomized placebo‐controlled study of the efficacy and safety of pirlindole, a reversible monoamine oxidase A inhibitor, in the treatment of depression
The efficacy and safety of pirlindole (300 mg/day), a new reversible inhibitor of monoamine oxidase A, have been evaluated in a… 
1993
1993
Lipid peroxidation affects catalytic properties of rat liver mitochondrial monoamine oxidases and their sensitivity to proteolysis.
1989
1989
Changes of Speech Activity in Depressed Patients under Pharmacotherapy
The reduced speech activity of depressed patients is a consistent finding in many systematic studies. However, this and other… 
1985
1985
On acute and chronic CNS effects of antidepressants in normals: neurophysiological, behavioral and pharmacokinetic studies with pirlindol.
In a double-blind placebo-controlled cross-over study the pharmacokinetic and pharmacodynamic properties of acutely and… 
1983
1983
Haemodynamic effects of pirlindole, a new tetracyclic antidepressant agent.
Cardiovascular dynamic, inotropic and electrophysiologic effects of the new tetracyclic antidepressant 2,3,3a,4,5,6-hexahydro-8… 
1982
1982
Pharmaco-EEG profiles of typical and atypical antidepressants.
Utilizing quantitative analysis of the human electroencephalogram (EEG), the effect of typical and atypical antidepressants on… 
1981
1981
Pharmacological properties of 2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino [3,2,1-j,k]carbazol hydrochloride (pirlindole), a new antidepressant.
The hydrochloride salt of 2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-j,k]carbazol hydrochloride (pirlindole) exerts… 
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