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piretanide

Known as: 4-phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid 
A sulfamoylbenzoic acid belonging to the class of loop diuretics. Piretanide is structurally related to furosemide and bumetanide.
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
&NA; The possible local peripheral and spinal (intrathecal) antinociceptive effect of Na+–K+–2Cl− cotransporter (NKCC) inhibitors… Expand
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Highly Cited
2002
Highly Cited
2002
Abstract. It is generally assumed that bumetanide possesses some selectivity for the renal Na-K-Cl cotransporter NKCC2, although… Expand
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Highly Cited
1998
Highly Cited
1998
The purpose of this study was to evaluate factors for improving the in vitro buoyancy and the drug release characteristics of… Expand
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1996
1996
A high-performance liquid chromatographic method with electrochemical detection (ED) has been developed for the determination of… Expand
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1993
1993
Sometimes novel treatments arise from chance observations made with existing drugs. The beneficial effects of an inhaled diuretic… Expand
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1990
1990
To modify the release rate of piretanide, a potent loop diuretic, a double-layer tablet was designed, and in vitro release was… Expand
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Highly Cited
1988
Highly Cited
1988
1. Neuropeptide Y (NPY), peptide YY (PYY) and, to a lesser extent, human pancreatic polypeptide (HPP) reduced short-circuit… Expand
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Highly Cited
1986
Highly Cited
1986
Intracellular Cl activity (aiCl), and intracellular pH (pHi) were measured in isolated sheep cardiac Purkinje fibres using a… Expand
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Highly Cited
1985
Highly Cited
1985
We used clearance and free-flow micropuncture techniques to evaluate the influence of several diuretic agents, given both… Expand
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Highly Cited
1983
Highly Cited
1983
The group of “high ceiling” diuretics consists of a variety of chemically different potent diuretic and saluretic substances… Expand
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