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piquindone

Known as: 2,6-dimethyl-3-ethyl-4,4a,5,6,7,8,8a,9-octahydro-4a,8a-1H-pyrrolo(2,3g)isoquinolin-4-one, 3-ethyl-2,6-dimethyl-4,4a,5,6,7,8,8a,9-octahydro-4a,8a-1H-pyrrolo(2,3g)isoquinolin-4-one 
National Institutes of Health

Papers overview

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Review
2012
Review
2012
Tourette’s disorder is a neuropsychiatric disorder characterised clinically by motor and vocal tics, which may be associated to… 
1989
1989
SummaryMolecular graphic design coupled with PCILO and crystallographic results have been used to investigate the three… 
1989
1989
A combination of experimental and theoretical methods were used to investigate the stereoelectronic structure of zetidoline, a… 
1987
1987
Piquindone (RO22-1319), a new "atypical" neuroleptic, was administered for 2 weeks to 37 schizophrenic patients, and the effects… 
1987
1987
The structure of the potent dopamine‐D2 antagonist, raclopride, (S)‐3,5‐dichloro‐N‐[(1‐ethyl‐2‐pyrrolidinyl)methyl]‐6… 
Highly Cited
1986
Highly Cited
1986
The ability of dopamine agonists and antagonists to compete with [3H]spiperone binding to rat striatal membrane preparations at 4… 
1986
1986
We have hypothesized that symptoms of Tourette Syndrome (TS) may represent D2 (dopamine-2) receptor hyperactivity. We treated 4… 
Highly Cited
1985
Highly Cited
1985
  • S. Stahl
  • Archives of general psychiatry
  • 1985
  • Corpus ID: 41349087
It is now 30 years since the introduction of neuroleptics into clinical practice, and we are still learning more about the… 
1984
1984
Ro 22-1319, a novel pyrroloisoquinoline compound, is a potent antipsychotic agent with low potential for extrapyramidal effects…