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Granulosa cell tumors of the ovary: prognostic factors and outcome.
The total survival with granulosa and theca cell tumors of the ovary is better than that with epithelial ovarian cancer as the hormonal symptoms make an early diagnosis possible and the mitotic rate is the most important prognostic factor at treatment planning. Expand
Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors.
Carbon-11-FLB 457 should be a useful PET ligand for quantitative examination of D2 dopamine receptors in extrastriatal regions in the human brain. Expand
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation
The data suggest that CRTH2 antagonism alone is effective in mouse allergic airway inflammation even to the extent that this mechanism can explain the efficacy of ramatroban. Expand
Randomized study on adjuvant chemotherapy in stage I high-risk ovarian cancer with evaluation of DNA-ploidy as prognostic instrument
The study was inconclusive as regards the question of adjuvant chemotherapy, and DNA-ploidy adds objective independent prognostic information regarding both DFS and DSS in early ovarian cancer. Expand
A systematic overview of chemotherapy effects in ovarian cancer.
A systematic review of chemotherapy trials in several tumour types was performed by The Swedish Council of Technology Assessment in Health Care (SBU), and there are preliminary data supporting the substitution of cisplatin with carboplatin. Expand
Binding characteristics of remoxipride and its metabolites to dopamine D2 and D3 receptors.
The present in vitro results suggest that the behavioural effects of remoxipride in rats may reflect the effect of remxipride and some of its high-affinity metabolites. Expand
A randomized phase-III study on adjuvant treatment with radiation (RT) {+/-} chemotherapy (CT) in early-stage high-risk endometrial cancer (NSGO-EC-9501/EORTC 55991)
A large number of patients with surgical stage I, II, IIIA, or IIIC cancer were eligible if they had a sufficiently high risk for micrometastatic disease to qualify for adjuvant therapy, while some patients had only one of these risk factors. Expand
Death rate and recurrence pattern among 841 clinical stage I endometrial cancer patients with special reference to uterine papillary serous carcinoma.
All UPSC patients with recurrence died of their malignancy compared to 61% of the ordinary adenocarcinoma patients, and 13 are alive with no known disease after treatment. Expand
A randomized, multicenter study comparing the efficacy and tolerability of tropisetron, a new 5‐HT3 receptor antagonist, with a metoclopramide‐containing antiemetic cocktail in the prevention of
Antiemetic treatment is a mandatory adjunct in emetogenic chemotherapy and one of the most disturbing side effects in cancer therapy. Expand
A physicogenetic method to assign ligand-binding relationships between 7TM receptors.
A computational protocol has been devised to relate 7TM receptor proteins (GPCRs) with respect to physicochemical features of the core ligand-binding site as defined from the crystal structure ofExpand