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piperazinedione

Known as: 2,5-piperazinedione, 3, 6-bis(5-chloro-2-piperidinyl)-, dihydrochloride, [3S-[3alpha(2S*,5R*),6alpha(2S*,5R*)]]- (9CI), PZD 
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione… 
National Institutes of Health

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593A
NCIt Antineoplastic Agent Terminology

Papers overview

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2015
2015
Biased assembly of the nuclear pore complex is required for somatic and germline nuclear differentiation in Tetrahymena
Ciliates have two functionally distinct nuclei, a somatic macronucleus (MAC) and a germline micronucleus (MIC) that develop from… 
Highly Cited
2005
Highly Cited
2005
Does assisted hatching improve implantation rates after in vitro fertilization or intracytoplasmic sperm injection in all patients? A prospective randomized study
AbstractPurpose: Preliminary data from some research centers indicate that assisted hatching might be of value to increase embryo… 
Review
2002
Review
2002
Recent advances in human sperm pathology.
1998
1998
Practice Committee Report
I n vivo hatching of the blastocyst is a critical component of the physiologic events culminating in implantation. Conversely… 
1998
1998
The impact of cellular fragmentation induced experimentally at different stages of mouse preimplantation development.
It has been demonstrated previously that removal of acellular debris from the preimplantation mouse embryo is beneficial for… 
Highly Cited
1991
Highly Cited
1991
Microsurgical fertilization and teratozoospermia.
Semen parameters were correlated with the outcome of partial zona dissection (PZD) in 42 couples with male factor infertility… 
Highly Cited
1991
Highly Cited
1991
Routine application of partial zona dissection for male factor infertility.
Partial zona dissection (PZD) increases the chances of fertilization by improving the access of spermatozoa to the perivitelline… 
Highly Cited
1979
Highly Cited
1979
AUTOLOGOUS BONE-MARROW TRANSPLANTATION IN RELAPSED ADULT ACUTE LEUKÆMIA
Review
1978
Review
1978
Patterns of resistance and therapeutic synergism among alkylating agents.
Alkylating anticancer drugs are varied in chemical structure, alkylating moieties, and likely mechanisms of cytotoxic activity… 
Highly Cited
1977
Highly Cited
1977
Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… 
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