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piperazinedione

Known as: 2,5-piperazinedione, 3, 6-bis(5-chloro-2-piperidinyl)-, dihydrochloride, [3S-[3alpha(2S*,5R*),6alpha(2S*,5R*)]]- (9CI), PZD 
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione… Expand
National Institutes of Health

Papers overview

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2015
2015
A pair of new enantiomeric alkaloid dimers, (+)- and (-)-pestaloxazine A (1), with an unprecedented symmetric spiro[oxazinane… Expand
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2006
Highly Cited
2006
A meta-analytic study on effectiveness of behavioral and psychotherapeutic treatments for challenging behaviors in individuals… Expand
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2003
Highly Cited
2003
Modification of the hydantoin ring in the previously described lead compound 2a has led to the discovery of compound 12a… Expand
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Highly Cited
1997
Highly Cited
1997
Although cryopreservation of mouse spermatozoa has recently become available for use, as yet there are considerable differences… Expand
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Highly Cited
1994
Highly Cited
1994
The erbium-yttrium-aluminium-garnet (Er:YAG) laser has been applied to micromanipulation in humans. It was used in the… Expand
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1991
Highly Cited
1991
The present studies were performed to establish the effects of the size and number of artificial holes produced in the zona… Expand
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Highly Cited
1989
Highly Cited
1989
Partial zona dissection (PZD), a method using mechanical force to open the human zona pellucida, and zona drilling, which uses… Expand
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Highly Cited
1989
Highly Cited
1989
Partial zona dissection (PZD) of human oocytes facilitates sperm penetration through mechanically made holes in the zona… Expand
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Highly Cited
1989
Highly Cited
1989
Hatching in vitro was studied following zona drilling of 507 two-cell mouse embryos using three methods: 1) acidic Tyrode's (AT… Expand
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Highly Cited
1977
Highly Cited
1977
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… Expand
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