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pinaverium bromide

Known as: Morpholinium, 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, Bromide 
An orally available bromide salt form of pinaverium, a calcium channel blocker (CCB) with antispasmodic activity. Upon oral administration… 
National Institutes of Health

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Review
2004
Review
2004
Quaternary ammonium derivatives as spasmolytics for irritable bowel syndrome.
Quaternary ammonium derivatives such as cimetropium, n-butyl scopolammonium, otilonium and pinaverium bromide have been… 
2003
2003
Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats.
AIM To investigate the effect of pinaverium bromide, a L-type calcium channel blocker with selectivity for the gastrointestinal… 
2001
2001
Contraction of human colonic circular smooth muscle cells is inhibited by the calcium channel blocker pinaverium bromide.
UNLABELLED The effects of L-type calcium channel blockers (CCBs) selective for the gastrointestinal tract (pinaverium) or non… 
1994
1994
Meta‐analysis of smooth muscle relaxants in the treatment of irritable bowel syndrome
Aim: To assess the efficacy of smooth muscle relaxants in the treatment of patients with irritable bowel syndrome, a meta… 
1992
1992
Interaction of pinaverium (a quaternary ammonium compound) with 1,4‐dihydropyridine binding sites in rat ileum smooth muscle
1 The interaction of pinaverium bromide, a quaternary ammonium compound, with binding sites for (L‐type) calcium channel blockers… 
1991
1991
A comparison of the action of otilonium bromide and pinaverium bromide: study conducted under clinical control.
We studied 40 patients with irritable bowel syndrome (IBS) which received in a simple-blind fashion otilonium and pinaverium… 
1990
1990
Effects of pinaverium on voltage‐activated calcium channel currents of single smooth muscle cells isolated from the longitudinal muscle of the rabbit jejunum
1 Smooth muscle cells of the longitudinal muscle of the rabbit jejunum were dispersed by enzyme treatment and recordings of… 
1988
1988
INHIBITION OF THE COLONIC MOTOR RESPONSE TO EATING BY PINAVERIUM BROMIDE IN IRRITABLE BOWEL SYNDROME PATIENTS
Summary— The effect of pinaverium bromide on the colonic motor response to eating was investigated in 10 irritable bowel syndrome… 
1985
1985
Effects of pinaverium bromide and verapamil on the motility of the rat isolated colon
1 Pinaverium bromide was 30 times less potent than verapamil in inhibiting intraluminal pressure responses of in vitro rat… 
1981
1981
Inhibitory effect of pinaverium bromide on gastrointestinal contractile activity in conscious dogs.
The inhibitory effect of 4-(6-bromoveratryl)-4-(2-[2-(6,6-dimethyl-2-norpinyl)-ethoxy]-ethyl)-morpholinium hydroxide (pinaverium… 
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