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piflutixol

Known as: 6-fluoro-9-(3-(4-(2-hydroxyethyl)piperidino) propylidene)-2-trifluoromethyl-thioxanthene 
National Institutes of Health

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2 relations

Broader (2)

Antipsychotic AgentsThioxanthenes

Papers overview

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2009
2009
The pharmacology of a new potent, long acting neuroleptic, piflutixol.
Piflutixol, 6-fluoro-9-[3-(4-(2-hydroxyethyl)piperidino)propylidene]-2-trifluoromethyl-thioxanthene, has been shown to have… 
2009
2009
Neuroleptic blockade of the effect of various neurotransmitter substances.
The antagonistic effect of neuroleptics to acetylcholine, histamine, 5-HT, and noradrenaline was examined in various in vivo and… 
2009
2009
Effect of piflutixol on turnover of catecholamines in mouse brain and rat corpus striatum.
Dopamine metabolism in vivo was studied after treatment with piflutixol (6-fluoro-9-[3-(4-(2-hydroxyethyl)piperidino)propylidene… 
2004
2004
Flupentixol and dopamine receptor selectivity
In several publications on 3H-cis(Z)-flupentixol (3H-FPT) binding (Hyttel 1978a, b, 1980; Cross and Owen 1980) it is claimed that… 
1995
1995
D2 Receptor Antagonists Do Not Modify Guanine Nucleotide‐Sensitive Interactions Between Dopamine and D1 Dopamine Receptors Under In Vitro Conditions
Abstract: This study investigated possible D1/D2 interactions in rat and bovine striatal tissue by examining the effects of D2… 
Highly Cited
1984
Highly Cited
1984
Selective and stereospecific interactions of R-SK & F 38393 with [3H]piflutixol but not [3H]spiperone binding to striatal D1 and D2 dopamine receptors: comparisons with SCH 23390.
1981
1981
Differential reversal by scopolamine and THIP of the antistereotypic and cataleptic effects of neuroleptics.
1979
1979
Amphetamine anorexia: Antagonism by typical but not atypical neuroleptics
1979
1979
Neuroleptic influence on hyperthermia induced by 5-hydroxytryptophan and p-methoxy-amphetamine in MAOI-pretreated rabbits
Abstract5-Hydroxytryptophan (5-HTP) and p-methoxyamphetamine (p-MA) induced dose-dependent, lethal hyperthermia when applied… 
1978
1978
Dopamine-receptor binding and adenylate-cyclase activity in mouse striatal tissue in the supersensitivity phase after neuroleptic treatment
The specific binding of 3H-labelled haloperidol (3H-Hal) and the basal and dopamine-stimulated adenylate-cyclase activity in… 
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