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picumast

Known as: 2H-1-benzopyran-2-one, 7-(3-(4-((4-chlorophenyl)methyl)-1-piperazinyl)propoxy)-3,4-dimethyl-, dihydrochloride 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

CoumarinsHistamine H1 Antagonists

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1995
Review
1995
Therapeutic Options in Ocular Allergic Disease
SummaryThe term ocular allergy encompasses a group of diseases in which there is a high frequency of atopy, ocular itching… 
Review
1991
Review
1991
Pharmacokinetic interactions between theophylline and other medication (Part I).
Many drugs have been found to increase or decrease the clearance of theophylline, probably by interaction with one or more of the… 
1991
1991
The effects of picumast on human eosinophil and neutrophil activation
Picutnast, a benzylpiperazine residue-substituted coumarin derivative, is a new anti-allergic compound. It has protective… 
1990
1990
Lens safety study with Picumast dihydrochloride--a double masked study using the Scheimpflug method.
A double-masked study was performed to investigate a possible side effect of the antiallergic substance Picumast dihydrochloride… 
1989
1989
Inhibition of immunological histamine release from guinea pig lungs and other organs by mepyramine, ketotifen, and picumast in vivo.
The effect of mepyramine, ketotifen and picumast (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarin… 
1989
1989
Metabolism of picumast after administration of picumast dihydrochloride and antiallergic activity of the main metabolites.
The present experiments were carried out to elucidate the chemical structure and the pharmacological activity of the main… 
1989
1989
Pharmacokinetics of picumast after administration of 14C-picumast dihydrochloride in dogs, rats, rabbits and monkeys.
In dogs, rats, monkeys and rabbits, picumast (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarin ) is eliminated… 
1989
1989
Study of potential kinetic interactions of picumast dihydrochloride and theophylline in vitro and after oral administration in man.
The kinetic interaction of picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarin… 
1989
1989
Pharmacokinetics of picumast dihydrochloride in patients with liver cirrhosis.
In a randomized parallel group design the pharmacokinetics of picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl… 
1987
1987
Calmodulin antagonism: a pharmacological approach for the inhibition of mediator release from mast cells.
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