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phthalazine

National Institutes of Health

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Phthalazines

Papers overview

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2018
2018
Identification of enzymes responsible for dantrolene metabolism in the human liver: A clue to uncover the cause of liver injury
2018
2018
Synthesis and evaluation of novel dimethylpyridazine derivatives as hedgehog signaling pathway inhibitors.
2017
2017
Design, synthesis, structure-activity relationship and mechanism of action studies of a series of 4-chloro-1-phthalazinyl hydrazones as a potent agent against Leishmania braziliensis.
2013
2013
B-precursor leukemia Nanoscale liposomal formulation of a SYK P-site inhibitor against
http://bloodjournal.hematologylibrary.org/content/121/21/4348.full.html Updated information and services can be found at: (1412… 
Highly Cited
2004
Highly Cited
2004
Realization of unusual ligand binding motifs in metalated container molecules: synthesis, structures, and magnetic properties of the complexes [(LMe)Ni2(mu-L')]n+ with L'=NO3-, NO2-, N3-, N2H4…
A series of dinickel(II) complexes with the 24-membered macrocyclic hexaazadithiophenol ligand H(2)L(Me) was prepared and… 
2004
2004
Synthesis and characterization of Cu(2)(I,I), Cu(2)(I,II), and Cu(2)(II,II) compounds supported by two phthalazine-based ligands: influence of a hydrophobic pocket.
The copper coordination chemistry of two phthalazine-based ligands of differing steric bulk was investigated. A family of… 
Highly Cited
2000
Highly Cited
2000
PTK 787 / ZK 222584 , a Novel and Potent Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases , Impairs Vascular Endothelial Growth Factor-induced Responses and Tumor Growth…
PTK787/ZK 222584 (1-[4-chloroanilino]-4-[4-pyridylmethyl] phthalazine succinate) is a potent inhibitor of vascular endothelial… 
1998
1998
Biotransformation of isoquinoline, phenanthridine, phthalazine, quinazoline, and quinoxaline by Streptomyces viridosporus
Streptomyces viridosporus T7A (ATCC␣39115), during growth in tryptone/yeast extract broth, cometabolized five heterocyclic… 
1989
1989
Diurnal variation and melatonin induction of hepatic molybdenum hydroxylase activity in the guinea-pig.
1979
1979
The oxidation of azaheterocycles with mammalian liver aldehyde oxidase.
1. Isoquinoline, cinnoline, quinoxaline, quinazoline and phthalazine were incubated with preparations of rabbit liver aldehyde… 
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