phthalazine

Abstract Regarding the green chemistry's goals, silica-coated magnetite nanoparticles (MNPs) open up new avenue to introduce an… Expand

Inhibition of the Hedgehog (Hh) pathway targeting the Smoothened receptor has proven therapeutic benefit for the treatment of Hh… Expand

Nitrogen atom containing heterocyclic compounds, pyridazines, pyridazinones and phthalazines are important structural feature of… Expand

[reactions: see text] The synthesis of nitrogen-containing heterocycles from alkyl dihalides (ditosylates) and primary amines and… Expand

Novel transient receptor potential vanilloid 1 (TRPV1) receptor antagonists with various bicyclic heteroaromatic pharmacophores… Expand

PTK787/ZK 222584 (1-[4-chloroanilino]-4-[4-pyridylmethyl] phthalazine succinate) is a potent inhibitor of vascular endothelial… Expand

Malignant pleural effusion (PE) is associated with advanced human lung cancer. We found recently, using a nude mouse model, that… Expand

We synthesized various 4-benzylamino-1-chloro-6-substituted phthalazines (15) and 4-benzylamino-1-chloro-7-substituted… Expand

A series of phthalazine and 1,2,3-benzotriazine derivatives which have heterocyclylpiperidino groups was synthesized and tested… Expand

Pyrogen is the only substance which has been reported to increase significantly the renal blood flow in man. However, according… Expand