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phosphatidylinositol 5-phosphate

Known as: PTDINS5P, PtdIns-5-P, phosphatidylinositol-5-phosphate 
 
National Institutes of Health

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Phosphatidylinositol Phosphates

Papers overview

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Highly Cited
2013
Highly Cited
2013
Depletion of a Putatively Druggable Class of Phosphatidylinositol Kinases Inhibits Growth of p53-Null Tumors
Here, we show that a subset of breast cancers express high levels of the type 2 phosphatidylinositol-5-phosphate 4-kinases α and… Expand
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Review
2007
Review
2007
Pleckstrin homology (PH) domains and phosphoinositides.
  • M. Lemmon
  • Biochemical Society symposium
  • 2007
    • Corpus ID: 15528262
PH (pleckstrin homology) domains represent the 11th most common domain in the human proteome. They are best known for their… Expand
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Highly Cited
2006
Highly Cited
2006
PtdIns(5)P activates the host cell PI3‐kinase/Akt pathway during Shigella flexneri infection
The virulence factor IpgD, delivered into nonphagocytic cells by the type III secretion system of the pathogen Shigella flexneri… Expand
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Highly Cited
2003
Highly Cited
2003
Phosphatidylinositol-5-Phosphate Activation and Conserved Substrate Specificity of the Myotubularin Phosphatidylinositol 3-Phosphatases
Phosphoinositides control many different processes required for normal cellular function. Myotubularins are a family of… Expand
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Highly Cited
2003
Highly Cited
2003
The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation
Phosphatidylinositol-5-phosphate (PI-5-P) is a newly identified phosphoinositide with characteristics of a signaling lipid but no… Expand
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Highly Cited
2001
Highly Cited
2001
Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells.
Previous data suggest the existence of discrete pools of inositol lipids, which are components of a nuclear phosphoinositide (PI… Expand
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Highly Cited
2000
Highly Cited
2000
Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7.
Type II phosphatidylinositol phosphate kinases (PIPkins) have recently been found to be primarily phosphatidylinositol 5… Expand
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Highly Cited
1998
Highly Cited
1998
Phosphatidylinositol-4-phosphate 5-Kinase Localized on the Plasma Membrane Is Essential for Yeast Cell Morphogenesis*
Phosphatidylinositol 4,5-biphosphate (PtdIns(4,5)P2), an important element in eukaryotic signal transduction, is synthesized… Expand
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Highly Cited
1998
Highly Cited
1998
Type I Phosphatidylinositol-4-phosphate 5-Kinases Synthesize the Novel Lipids Phosphatidylinositol 3,5-Bisphosphate and Phosphatidylinositol 5-Phosphate*
Inositol phospholipids regulate a variety of cellular processes including proliferation, survival, vesicular trafficking, and… Expand
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Highly Cited
1997
Highly Cited
1997
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate
Phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2), a key molecule in the phosphoinositide signalling pathway, was thought to… Expand
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