phosphatidylinositol 5-phosphate

Known as: PTDINS5P, PtdIns-5-P, phosphatidylinositol-5-phosphate 
 
National Institutes of Health

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Phosphatidylinositol Phosphates

Papers overview

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2014
2014
Phosphatidylinositol 5-phosphate regulates invasion through binding and activation of Tiam1.
PtdIns5P is a lipid messenger acting as a stress-response mediator in the nucleus, and known to maintain cell activation through… (More)
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2014
2014
Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate.
UHRF1 is a multidomain protein crucially linking histone H3 modification states and DNA methylation. While the interaction… (More)
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2008
2008
Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate.
Phosphoinositide signaling pathways regulate numerous processes in eukaryotic cells, including migration, proliferation, and… (More)
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Highly Cited
2006
Highly Cited
2006
The Arabidopsis homolog of trithorax, ATX1, binds phosphatidylinositol 5-phosphate, and the two regulate a common set of target genes.
The Arabidopsis homolog of trithorax, ATX1, regulates numerous functions in Arabidopsis beyond the homeotic genes. Here, we… (More)
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Highly Cited
2004
Highly Cited
2004
Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells.
MTM1, the gene encoding myotubularin (MTM1), is mutated in the X-linked myotubular myopathy (XLMTM), a severe genetic muscular… (More)
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2004
2004
Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation.
The cellular functions and regulation of phosphatidylinositol (PtdIns) 5-phosphate (5-P), the newest addition to the family of… (More)
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2004
2004
Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice.
Phosphorylated derivatives of the lipid phosphatidylinositol are known to play critical roles in insulin response… (More)
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Highly Cited
2003
Highly Cited
2003
Phosphatidylinositol-5-Phosphate Activation and Conserved Substrate Specificity of the Myotubularin Phosphatidylinositol 3-Phosphatases
Phosphoinositides control many different processes required for normal cellular function. Myotubularins are a family of… (More)
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2000
2000
Thrombin stimulation of platelets causes an increase in phosphatidylinositol 5-phosphate revealed by mass assay.
Phosphatidylinositol 5-phosphate (PtdIns5P), a novel inositol lipid, has been shown to be the major substrate for the type II… (More)
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Highly Cited
1997
Highly Cited
1997
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate
Phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2), a key molecule in the phosphoinositide signalling pathway, was thought to… (More)
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