phosphatidylinositol 3-kinase signaling

Known as: phosphatidylinositol 3-kinase cascade, PI3K signal transduction, PI3K signaling 
A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface… (More)
National Institutes of Health

Papers overview

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2009
2009
Aberrant activity of the phosphatidylinositol 3-kinase (PI3K) pathway supports growth of many tumors including those of breast… (More)
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2007
2007
OBJECTIVE Contraction of cardiac myocytes is initiated by Ca(2+) entry through the voltage-dependent L-type Ca(2+) channel (LTCC… (More)
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2007
2007
The nuclear receptor corepressor (NCoR) regulates the activities of DNA-binding transcription factors. Recent observations of its… (More)
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Highly Cited
2006
Highly Cited
2006
Activation of the phosphatidylinositol 3-kinase (PI3K)-AKT/protein kinase B signaling pathway has been associated with multiple… (More)
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2006
2006
Essential fatty acids are not only energy-rich molecules; they are also an important component of the membrane bilayer and… (More)
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Highly Cited
2002
Highly Cited
2002
Vascular endothelial growth factor (VEGF) expression is upregulated by hypoxia-inducible factor-1 (HIF-1) in ischemic tissues and… (More)
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2002
2002
We report the characterization of two signal transduction proteins related to Bam32, known as TAPP1 and TAPP2. Bam32, TAPP1, and… (More)
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Highly Cited
2002
Highly Cited
2002
Transmembrane proteins of the tetraspanin superfamily are assembled in multimeric complexes on the cell surface. Spatial… (More)
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1999
Highly Cited
1999
The vacuolar protein sorting (VPS) pathway of Saccharomyces cerevisiae mediates transport of vacuolar protein precursors from the… (More)
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1997
Highly Cited
1997
Although it is known that many stimuli can activate mitogen-activated protein kinases (MAPKs) and phosphatidylinositol 3-kinases… (More)
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