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phosphatidylinositol 3-kinase complex

Known as: phosphatidylinositol 3-kinase complex location, phosphoinositide 3-kinase complex location, PI3K complex 
A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These… 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
ABSTRACT Autophagosome formation depends on a carefully orchestrated interplay between membrane-associated protein complexes… 
2019
2019
ABSTRACT Macroautophagy/autophagy plays key roles in development, oncogenesis, and cardiovascular and metabolic diseases… 
2019
2019
The activation of adenosine monophosphate-activated protein kinase (AMPK) in skeletal muscle coordinates systemic metabolic… 
Highly Cited
2014
Highly Cited
2014
The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) that functions in early autophagy consists of the lipid kinase… 
Highly Cited
2013
Highly Cited
2013
Atg38 provides a physical linkage between the Vps15–Vps34 and Atg14–Vps30 subcomplexes to facilitate PI3-kinase complex I… 
2013
2013
We have elucidated a novel mechanism through which the autophagy-specific class III phosphatidylinositol 3-kinase (PtdIns3K… 
Highly Cited
2012
Highly Cited
2012
Yeast vacuoles are large organelles that fragment and fuse in response to environmental conditions, such as changes in osmotic… 
Highly Cited
2001
Highly Cited
2001
Autophagy is an intracellular bulk protein degradation system. Beclin is known to be involved in this process; however, its role… 
1996
1996
Ligand stimulation of the platelet-derived growth factor (PDGF) receptor results in its association with phosphoinositide 3… 
Highly Cited
1992
Highly Cited
1992
PtdIns 3-kinase associates with certain activated protein-tyrosine kinase receptors and with the pp60c-src/polyoma middle-T…