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peptidylglycine monooxygenase activity

Known as: peptidylglycine 2-hydroxylase activity, peptidyl alpha-amidating enzyme activity, PAM-A 
Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O. [EC:1.14.17.3]
National Institutes of Health

Papers overview

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2016
2016
Expression of recombinant human bifunctional peptidylglycine α-amidating monooxygenase in CHO cells and its use for insulin analogue modification.
2015
2015
Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal Cuproenzyme*
Background: Trafficking of Atp7a, a copper pump, and PAM-1, a cuproenzyme, depends on adaptor protein-1 complex (AP-1). Results… 
2012
2012
Production of the catalytic core of human peptidylglycine α-hydroxylating monooxygenase (hPHMcc) in Escherichia coli.
2007
2007
Induction of peptidylglycine α-hydroxylating monooxygenase activity by nerve growth factor in PC12 cells
Pheochromocytoma PC12 cells grown in the presence of nerve growth factor (NGF) undergo marked neuronal differentiation. During… 
2006
2006
Models for dioxygen activation by the CuB site of dopamine β-monooxygenase and peptidylglycine α-hydroxylating monooxygenase
On the basis of spectroscopic and crystallographic data for dopamine β-monooxygenase and peptidylglycine α-hydroxylating… 
2001
2001
The Membrane-bound Bifunctional Peptidylglycine a-Amidating Monooxygenase Protein
The biosynthesis of a-amidated peptides from their glycine-extended precursors is catalyzed by the sequential action of… 
2001
2001
Membrane-associated Forms of Peptidylglycine a-Amidating Monooxygenase Activity in Rat Pituitary TISSUE
Membrane-associated peptidylglycine a-amidating monooxygenase (PAM) activity was investigated in rat anterior and… 
1999
1999
Characterization and regulation of peptidylglycine α-amidating monooxygenase (PAM) expression in H9c2 cardiac myoblasts
Abstract. Peptidylglycine α-amidating monooxygenase (PAM), which catalazyes the two-step formation of bioactive α-amidated… 
1997
1997
Estrogen Regulation of Peptidylglycine α-Amidating Monooxygenase Messenger Ribonucleic Acid Levels by a Nuclear Posttranscriptional Event.
Peptidylglycine α-amidating monooxygenase (PAM; EC 1.14.17.3) is a bifunctional protein containing two enzymes that act… 
1993
1993
Structure‐Activity Relationships among Inhibitors of Peptidylglycine Amidating Monooxygenase
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